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Merck
CN

C1540000

氯己定 二盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

1,6-双(N5-[对氯苯基]-N1-双胍)己烷;1,1′-己基双(5-[对氯苯基]双胍), 洗必泰

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关于此项目

经验公式(希尔记法):
C22H30Cl2N10 · 2HCl
化学文摘社编号:
分子量:
578.37
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

chlorhexidine

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10.2ClH/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;;/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H

InChI key

WJLVQTJZDCGNJN-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorhexidine dihydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Daily chlorhexidine bathing and hospital-acquired infection.
Jean-Jacques Parienti et al.
The New England journal of medicine, 368(24), 2331-2331 (2013-06-14)
Patricia Conley et al.
Nursing, 43(7), 18-23 (2013-06-20)
Several studies have demonstrated that oral care with chlorhexidine gluconate (CHG) 0.12% solution reduces the incidence of ventilator-associated pneumonia (VAP) in mechanically ventilated patients with endotracheal tubes in the ICU. Minimal evidence shows the effectiveness of any oral care protocols
Maristela Dutra-Correa et al.
The journal of adhesive dentistry, 15(3), 287-292 (2013-04-06)
This study tested the hypothesis that 2% chlorhexidine (CHX) does not affect the 18-month clinical performance of two dentin adhesives, XP Bond (XPB) and XENO V (XEN). A total of 120 noncarious cervical lesions (NCCL) were selected and assigned to



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货号GTIN
C154000004061833792322