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Merck
CN

M1845000

美曲磷酯

European Pharmacopoeia (EP) Reference Standard

别名:

三氯磷酸酯, (2,2,2-三氯-1-羟乙基)磷酸二甲酯, 美曲磷酯

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关于此项目

经验公式(希尔记法):
C4H8Cl3O4P
化学文摘社编号:
分子量:
257.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1709434
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grade

pharmaceutical primary standard

API family

trichlorfon, metrifonate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COP(=O)(OC)C(O)C(Cl)(Cl)Cl

InChI

1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3

InChI key

NFACJZMKEDPNKN-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metrifonate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

农药列管产品
危险化学品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J M Ringman et al.
The Journal of clinical psychiatry, 60(11), 776-782 (1999-12-10)
To review preclinical and clinical studies of metrifonate, a cholinesterase inhibitor relevant to the treatment of Alzheimer's disease. English-language literature identified by MEDLINE using the term metrifonate was reviewed, and bibliography-sorted searches were conducted. Metrifonate is an organophosphate cholinesterase inhibitor
Metrifonate.
H M Lamb et al.
Drugs & aging, 11(6), 490-496 (1997-12-31)
Graziele Daiane Stürmer et al.
Ecotoxicology and environmental safety, 109, 56-62 (2014-08-29)
Organophosphate (OP) insecticides have been used indiscriminately, based on their high dissipation rates and low residual levels in the environment. Despite the toxicity of OPs to beneficial insects is principally devoted to the acetylcholinesterase (AChE) inhibition, the physiological mechanisms underlying



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货号GTIN
M184500004061833812822