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关于此项目
经验公式(希尔记法):
C22H24ClN3O · HCl
化学文摘社编号:
分子量:
418.36
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0000326, traceable to USP 1046158
API family
azelastine
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
Cl.CN1CCCC(CC1)N2N=C(Cc3ccc(Cl)cc3)c4ccccc4C2=O
InChI
1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
InChI key
YEJAJYAHJQIWNU-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Azelastine Hydrochloride is a long-acting antiallergic and antiasthmatic drug.
Azelastine Hydrochloride is a long-acting antiallergic and antiasthmatic drug.
Application
Azelastine Hydrochloride may be used as a pharmaceutical secondary reference standard for the determination of azelastine in plasma samples by manual-injection liquid chromatographic method using fluorescence detection.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
H1 组胺受体拮抗剂;NF-kB 激活剂。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA5303 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs
Chand N, et al.
Allergy, 41(7), 473-478 (1986)
Determination of azelastine and desmethylazelastine in human plasma by high-performance liquid chromatography
Pivonka J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 420(7), 89-98 (1987)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| PHR1636-1G | 04061834793212 |
