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Y0000443

氟尼辛葡甲胺

Name: 氟尼辛葡甲胺
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

2-[[2-甲基-3-（三氟甲基）苯基]氨基] -3-吡啶羧酸葡甲胺盐, 氟尼辛甲葡胺

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关于此项目

经验公式（希尔记法）:

C₁₄H₁₁F₃N₂O₂·C₇H₁₇NO₅

化学文摘社编号:

42461-84-7

分子量:

491.46

NACRES:

NA.24

PubChem Substance ID:

329830960

UNSPSC Code:

41116107

MDL number:

MFCD01725419

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属性

grade

pharmaceutical primary standard

API family

flunixin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F

InChI

1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1

InChI key

MGCCHNLNRBULBU-WZTVWXICSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

氟尼辛葡甲胺（IC₅₀ = 1 nM）可用作动物药物，用于治疗马的肠缺血、绞痛和内毒素血症。

Biochem/physiol Actions

COX1、COX2 和 PLA2 抑制剂非麻醉性镇痛、解热、抗炎。

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The effects of a novel anti-inflammatory compound (AHI-805) on cyclooxygenase enzymes and the recovery of ischaemia injured equine jejunum ex vivo.

J F Marshall et al.

Equine veterinary journal. Supplement, (39)(39), 106-111 (2011-08-04)

Flunixin meglumine is used for treatment of equine colic despite evidence of inhibited recovery of mucosal barrier function following small intestinal ischaemic injury. This study aimed to characterise an alternative treatment (AHI-805) for abdominal pain in the horse. To determine

Ultrasound characteristics of experimentally induced luteinized unruptured follicles (LUF) and naturally occurring hemorrhagic anovulatory follicles (HAF) in the mare.

J Cuervo-Arango et al.

Theriogenology, 77(3), 514-524 (2011-10-01)

The development of hemorrhagic anovulatory follicles (HAF) involves luteinization and hemorrhage of the follicle. This is observed on ultrasound as an increase in the echogenicity of the granulosa layer and formation of echoic particles in the antrum. The inhibition of

Pharmacokinetic interactions of flunixin meglumine and doxycycline in broiler chickens.

F Yang et al.

Journal of veterinary pharmacology and therapeutics, 36(1), 85-88 (2012-02-02)

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货号	GTIN
Y0000443	04061837568596