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Organolithium Reagents

Sure/Seal包装的有机锂试剂

自从被Schlenk和Holtz发现以来，锂化化学已成为现代工业合成中的一项成熟技术。随着对合成高度复杂的天然产物并获得新型化学结构以探测化学领域中未知领域的需求产生，有机锂试剂已成为形成已知键（例如亲核加成和取代）和开发有机合成新技术中必不可少的元素。

作为强碱和亲核试剂的有机锂化合物，在有机合成中作为关键的中间体和强大的试剂展现出了突出的重要性。

应用举例：

  • 有机锂试剂常参与到交叉偶联反应中。
  • 丁基锂异构体正丁基锂，手性仲丁基锂和叔丁基锂已分别作为聚合引发剂、仲丁基碳负离子源和Grignard反应中的强碱而广泛用于有机合成。
  • 高度立体化学富集的有机锂化合物是立体选择性合成中多功能且备受青睐的合成中间体。

由于有机锂试剂对空气和湿气都高度敏感，因此我们提供了高质量的Sure/Seal™瓶包装，以延长这些试剂的使用寿命。更小尺寸的瓶包装需要更少的针头进入来进行试剂量消耗。因此，我们多种有机金属试剂也正在过渡到专用的25 mL Sure/Seal™包装，以减少浪费和更为不稳定试剂的分解。

探索我们的有机锂试剂如何在您的科学发现中发挥作用。

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相关产品类别
Grignard Reagents
Our unparalleled portfolio of Grignard Reagents are used in reactions such as Grignard reaction to form a new carbon-carbon bond.
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C–H Functionalization
C–H functionalization is the reliable and predictable conversion of a C–H into a C–C, C–N, C–O, or C–X bond in a selective and controlled fashion.
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Cross-coupling is a common reaction in organic chemistry for the creation of C-C, C-N, and C-O bonds with the aid of a metal catalyst.
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Fluorination is the introduction of fluorine to a compound via electrophilic fluorination, nucleophilic fluorination, difluoromethylation, trifluoromethylation, or perfluoroalkylation.
Metathesis
Olefin metathesis involves an organic reaction that redistributes fragments of alkenes (olefins) by cleavage and transformation of carbon-carbon double bonds.
Photocatalysis
Photoredox catalysis utilizes photocatalysts in the presence of visible light to form an array of synthetic transformations including, but not limited to, cross-coupling, C-H functionalization, alkene and arene functionalization, and trifluoromethylation.
Organic Reaction Toolbox
An organic reaction toolbox provides structure-activity relationships for unique chemical reactions to optimally design and control small molecule synthesis.
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