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Kevin D Cashman et al.
The Journal of nutrition, 144(7), 1050-1057 (2014-05-16)
Fundamental knowledge gaps in relation to the 3 epimer of 25-hydroxycholecalciferol [3-epi-25(OH)D₃] limit our understanding of its relevance for vitamin D nutrition and health. The aims of this study were to characterize the 3-epi-25(OH)D₃ concentrations in a nationally representative sample
Yoon Ji Kim et al.
Endocrine journal, 60(2), 179-184 (2012-10-16)
Vitamin D is an important regulator of bone health. Previous studies examining the association between vitamin D deficiency and osteoporotic fractures have reported conflicting results. The relationship between vitamin D status and risk of vertebral fractures in diabetic patients is
Maha Hoteit et al.
Metabolism: clinical and experimental, 63(7), 968-978 (2014-05-31)
The aim of the current study is to investigate the prevalence of hypovitaminosis D in Lebanese subjects, its robust predictors, evaluate the relationship between 25 hydroxy vitamin D [25(OH)D] and parathyroid hormone levels, and derive desirable vitamin D levels, based
Amin Salehpour et al.
Nutrition journal, 11, 78-78 (2012-09-25)
Vitamin D concentrations are linked to body composition indices, particularly body fat mass. Relationships between hypovitaminosis D and obesity, described by both BMI and waist circumference, have been mentioned. We have investigated the effect of a 12-week vitamin D3 supplementation
Corinne D Engelman et al.
The Journal of nutrition, 143(1), 17-26 (2012-11-30)
Vitamin D deficiency {defined by the blood concentration of 25-hydroxyvitamin D [25(OH)D]} has been associated with many adverse health outcomes. Genetic and nongenetic factors account for variation in 25(OH)D, but the role of interactions between these factors is unknown. To
Livia Melo Villar et al.
World journal of gastroenterology, 19(35), 5917-5924 (2013-10-15)
To evaluate the association between 25-hydroxyvitamin D [25(OH)D] and sustained virological response (SVR) in hepatitis C virus (HCV) infected individuals. Relevant studies were identified by systematically searching MEDLINE databases up to March 2012 and abstracts of the European and American
P Adamczyk et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 47(12), 873-879 (2015-07-03)
Changes in body weight, waist and hip circumferences, body composition, and skeletal status in women after bariatric surgery were evaluated. Thirty-six women [mean age 41.2 ± (SD) 9.5 years, weight 115.7±18.0 kg, and BMI 42.1±5.3 kg/m(2)] underwent laparoscopic sleeve gastrectomy. Bone mineral density
Kanitpong Phabphal et al.
Epilepsia, 54(2), 249-255 (2013-01-04)
This study sought to determine the association between BsmI polymorphism and bone mineral density, 25-hydroxyvitamin D, and parathyroid hormone levels in patients with epilepsy. We recruited ambulatory young adults with epilepsy who were taking phenytoin. Data regarding demographics, basic laboratory
Janna Nissen et al.
The American journal of clinical nutrition, 101(1), 218-227 (2014-12-21)
Little is known about how the genetic variation in vitamin D modulating genes influences ultraviolet (UV)B-induced 25-hydroxyvitamin D [25(OH)D] concentrations. In the Food with vitamin D (VitmaD) study, we showed that common genetic variants rs10741657 and rs10766197 in 25-hydroxylase (CYP2R1)
Alexander Ströhle et al.
Inflammation & allergy drug targets, 10(1), 54-63 (2010-12-28)
As elements of the antioxidant system, cofactors of enzymes, components of transcription factors, and epigenetic modulators, micronutrients, such as vitamins and trace elements, influence various metabolic processes that are directly associated with immune functions. Specifically, the vitamins C and D
Tarja Nurmi et al.
Analytical biochemistry, 435(1), 1-9 (2013-01-01)
The diode array detector in our high-performance liquid chromatography (HPLC) method for 25-hydroxyvitamin D(3) (25OHD(3)) and 25-hydroxyvitamin D(2) (25OHD(2)) did not perform satisfactorily for measuring human serum concentrations below 30nM. Because of a need for a reliable self-managed method in
Vitamin D status and effect of low-dose cholecalciferol and high-dose ergocalciferolsupplementation in multiple sclerosis.
Hiremath GS, Cettomai D, Baynes M, et al.
Clinical Immunology (Orlando, Fla.), 15, 735-740 (2009)
Stephen J Bruce et al.
Rapid communications in mass spectrometry : RCM, 27(1), 200-206 (2012-12-15)
The aim of the work was to develop and validate a method for the quantification of vitamin D metabolites in serum using ultra-high-pressure liquid chromatography coupled to mass spectrometry (LC/MS), and to validate a high-resolution mass spectrometry (LC/HRMS) approach against
K M Carnagey et al.
Journal of animal science, 86(7), 1637-1648 (2008-03-18)
The objective of this trial was to determine how 25-hydroxyvitamin D(3) (25-OH D(3)) supplementation, altering supplemental dietary calcium, or their combination influence postmortem biochemical and tenderness changes in muscles from the round of mature cows. Twenty-seven Angus cows (3 to
Jim Bartley
Expert review of anti-infective therapy, 8(12), 1359-1369 (2010-12-08)
In the preantibiotic era, TB of the skin was treated successfully with UV light. By the 1920s, pulmonary TB was being treated with regular sun exposure. During the last decade, basic laboratory research into the antimicrobial actions of vitamin D
Grant R Campbell et al.
PLoS pathogens, 8(11), e1003017-e1003017 (2012-11-21)
Toll-like receptors (TLR) are important in recognizing microbial pathogens and triggering host innate immune responses, including autophagy, and in the mediation of immune activation during human immunodeficiency virus type-1 (HIV) infection. We report here that TLR8 activation in human macrophages
Jessy El Hayek et al.
The Journal of nutrition, 143(2), 154-160 (2012-12-21)
The 2007 to 2009 Canadian Health Measures Survey reported vitamin D status in a representative sample of Canadians (6-79 y); however, children <6 y were not assessed. Our objective was to measure vitamin D intake from food and supplements, sun
Uttam Garg et al.
Journal of clinical laboratory analysis, 26(5), 349-357 (2012-09-25)
Vitamin D plays a vital role not only in bone health but also in pathophysiology of many other body functions. In recent years, there has been significant increase in testing of 25-hydroxyvitamin D (25-OH vitamin D), a marker of vitamin
Calcium and vitamin D: skeletal and extraskeletal health.
Khazai N, Judd SE, Tangpricha V.
Current Rheumatology Reports, 10, 10-117 (2008)
Evaluation of the cross-reactivity of 25-hydroxyvitamin D2 on seven commercial immunoassays on native samples.
Caroline Le Goff et al.
Clinical chemistry and laboratory medicine, 50(11), 2031-2032 (2012-10-26)
Laura A G Armas et al.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 21(2), 134-139 (2011-01-18)
The understanding of vitamin D's role in human health has recently expanded. It is now recognized as more than a hormone activated in the kidney only for calcium homeostasis. It is metabolized and used by virtually every cell in the
Maarten W Taal et al.
Kidney international, 86(2), 407-413 (2014-01-17)
Fibroblast growth factor (FGF) 23 is an important regulator of phosphaturia. Its serum level was found to increase before that of parathyroid hormone (PTH) in early chronic kidney disease (CKD) in some but not all previous studies. As vitamin D
Eun Young Choi
Asia Pacific journal of clinical nutrition, 21(4), 526-535 (2012-09-29)
Vitamin D deficiency is a global health problem that is associated with increased risks of major diseases. This study investigated the status of 25-hydroxyvitamin D [25(OH)D] and its demographic and lifestyle determinants among Korean adults. A total of 5,847 adults
Should family physicians routinely screen for vitamin D deficiency? No: screening is unnecessary, and routine supplementation makes more sense.
Colin Kopes-Kerr
American family physician, 87(8), od2-od2 (2013-05-15)
Cécile Meunier et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 989, 54-61 (2015-03-25)
Many methods for routine total plasma/serum 25-hydroxyvitamin D (25OHD) measurements are available from automated immunoassays to the most specific LC-MS/MS techniques. These last ones are nowadays numerous, still perfectible but more powerful than immunoassays in specific illnesses. We presented a
Ulrike Lehmann et al.
The Journal of clinical endocrinology and metabolism, 98(11), 4339-4345 (2013-09-05)
The bioequivalence of the different forms of vitamin D, ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), has been questioned. Earlier studies have suggested that vitamin D2 is less biologically active than vitamin D3. In a parallel study, we tested the
M R Pinzone et al.
European review for medical and pharmacological sciences, 17(14), 1938-1950 (2013-07-24)
Vitamin D deficiency is very common among HIV-infected subjects. We cross-sectionally evaluated the prevalence and risk factors for hypovitaminosis D in 91 HIV-infected Italian patients. We studied in a cohort of 91 HIV-infected Italian patients the metabolism of Vitamin D
J Dayre McNally et al.
The Journal of clinical endocrinology and metabolism, 98(5), E877-E881 (2013-04-03)
Recent studies in critically ill populations have suggested both adrenal insufficiency (AI) and vitamin D deficiency to be associated with worse clinical outcome. There are multiple mechanisms through which these pleiotropic hormones might synergistically influence critical illness. The aim of
Peter F Schnatz et al.
Clinical chemistry, 60(4), 600-609 (2013-11-07)
Supplementation with vitamin D has received attention as a potential cardioprotective strategy. Biologically plausible mechanisms have been proposed to link vitamin D to coronary heart disease (CHD) prevention, and observational studies suggest an inverse association between serum 25-hydroxyvitamin D (25OHD)
Zengliu Su et al.
Clinica chimica acta; international journal of clinical chemistry, 417, 62-66 (2012-12-26)
The circulating form of vitamin D, 25-Hydroxyvitamin D (25-OHD), is commonly measured in clinical labs to evaluate vitamin D status of an individual. Vitamin D exists in 2 major forms: vitamin D3 and D2. Current methodologies for 25-OHD testing include
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