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Cell signaling

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facet applications:Cell signaling
facet content type:Technical Article
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Tec
Tec kinases represent the second largest family of nonreceptor tyrosine kinases and are activated in response to cellular stimulation by antigen receptors, integrins, growth factors, cytokines and G protein-coupled receptors.
Laminin
laminin
PDGFR
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Lysophospholipid Receptors
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GRKs
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FGFR
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FAK
The focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase that distinctly co-localizes with integrins at sites of attachment to their ligands.
Cytokine Receptors (Hematopoetin Receptor Family)
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Protein Prenyltransferases
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Sensor Dyes
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
磷脂酶A2
磷脂酶A2(PLA2)代表的是一类可水解甘油磷脂的sn-2酯以产生脂肪酸和溶血磷脂的酶。目前已知的是,其中一些酶可在哺乳动物细胞中释放花生四烯酸以用于类花生酸的生物合成,因此PLA2抑制剂的开发引起了相当大的兴趣。基于氨基酸序列,现有超过12种不同的哺乳动物PLA2以及多种非哺乳动物的形式,它们被归类为具有多个亚组的14个组别。
PKC
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Nuclear Receptors (PPARs)
Peroxisome proliferator activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors that are related to retinoid, steroid and thyroid hormone receptors.
钾通道
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InsR
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Chemokine Receptors
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Vascular Endothelial Growth Factors (VEGF)
Vascular endothelial growth factor (VEGF) is a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF-A (VEGF) is a potent growth factor for blood vessel endothelial cells, showing pleiotropic
线粒体应激和ROS
氧化应激,在一部分上,是由多种细胞过程产生的活性氧介导,并由诸如酶清除剂或抗氧化剂调节剂等细胞抗氧化剂机制所控制的。自由基,如活性氧,会通过细胞引起细胞损伤。
Tropomyosin
Tropomyosin together with troponin, regulate the binding of myosin to actin. Tropomyosin is a dimeric coiled-coil protein forming continuous polymers along the myosin-binding groove of actin. Varoius tropomyosin isoforms help to confer structure and function to actins in the
肌球蛋白(Myosin)
肌球蛋白是ATP依赖性运动蛋白家族。肌球蛋白II是真核肌肉收缩的主要收缩蛋白,通过沿着肌动蛋白微丝“行走”参与肌肉收缩。
腺苷酸环化酶
腺苷酸环化酶在整个动物界都存在,并在细胞调节中发挥不同的作用。在细菌中,如百日咳博德特氏菌、炭疽芽孢杆菌、铜绿假单胞菌或鼠疫杆菌的腺苷酸环化酶,可以响应于营养物而受到调节,或者它可以构成哺乳动物中的毒性因子。
Interleukin Family (IL)
The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and
Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels
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Transient Receptor Potential Channels
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Src
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N-连接聚糖
N-连接聚糖、修饰和降解
钠通道
电压门控钠通道存在于大多数可兴奋细胞膜中,在产生动作电位方面起着重要作用。
Actinin
Introduction about α-Actinin protein present in both muscle and non-muscle cells.
核-受体-类固醇
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