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Organic reaction toolbox

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Heck反应
Heck反应是烯烃与芳基或乙烯基卤化物(或三氟甲磺酸酯)之间的钯催化交叉偶联反应,用于生成取代的烯烃。
Synthia™ Organic Retrosynthesis Software - Resources
Learn more about Synthia™ Organic Retrosynthesis Software and view a list of publications
Spirocyclic Building Blocks for Scaffold Assembly
Spirocyclic modules containing four-membered rings are currently of growing interest to discovery chemists.
VSEPR Chart | Valence Shell Electron Pair Repulsion Theory
Use our handy VSEPR chart to find the 3-D geometric VSEPR shapes of molecules and ions. Learn about VSEPR theory and shapes like trigonal planar or square pyramidal. VSEPR stands for valence shell electron pair repulsion.
Aldehydes - Types & Structure
Technical article regarding Aldehydes - Types & Structure
傅-克酰基化反应
傅-克酰基化反应是一种芳烃与酰氯或酸酐使用强路易斯酸催化剂的反应。该反应通过亲电芳族取代进行,形成单酰化产物。
Protected Carbohydrate Building Blocks for More Efficient Syntheses
Carbohydrates and their biologically active glycoconjugate analogs are emerging as an important class of biomolecules.
Fries重排
Fries重排反应是一类重要的有机人名反应,它涉及在催化剂存在下加热时将酚酯转化成邻位或对位酰基酚。适用于该反应的催化剂是布朗斯特酸或路易斯酸,如HF、AlCl3、BF3、TiCl4或SnCl4。Fries重排反应为邻位、对位选择性反应,用于酰基酚的制备。这种有机反应以德国化学家Karl Theophil Fries的名字命名。
Reagents for the Mitsunobu Reaction
One of the most powerful and widely used carboncarbon bond forming reactions in organic synthesis is the Mitsunobu reaction.
Ugi Reaction
The Ugi reaction (Scheme 1) is an isonitrile-based MCR that provides a rapid route for the preparation of a-aminoacyl amide derivatives. The Ugi 4 component condensation of an amine, oxo compound, carboxylic acid and an isocyanide is the most documented
Diels–Alder Reaction
The Diels–Alder reaction is the reaction between a conjugated diene and an alkene (dienophile) to form unsaturated six-membered rings. Since the reaction involves the formation of a cyclic product via a cyclic transition state, it is also referred to as
Periodic Table of the Elements
Download the Periodic Table of the Elements with names, atomic mass and number in printable .pdf and image format. Use the periodic table chart by element names in alphabetical order for quick research, reference and lab use. From MilliporeSigma.
Unnatural Amino Acids
Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.
Inverse Electron Demand Diels–Alder Reactions of 1,2,4,5-Tetrazines and 1,2,3-Triazines
The inverse electron demand Diels-Alder reactions of electron-deficient heterocycles are significant cycloaddition reactions for the total synthesis of natural products containing highly substituted and functionalized heteroaromatic ring systems.
1-hydrosilatrane
As a versatile hydride reagent, 1-hydrosilatrane can be used in reduction reactions to synthesize alcohols, amines, their chiral counterparts, and esters from aldehydes/ketones.
Biginelli Reaction
The Biginelli Reaction is an acid catalyzed, threecomponent reaction between an aldehyde, b-ketoester, and urea that produces tetrahydropyrimidones, which have potential pharmaceutical applications.
Knoevenagel Condensation Reaction
Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.
Schlenk Type Glassware
Schlenk Type Glassware
Ugi Reaction
The Ugi reaction (Scheme 1) is an isonitrile-based MCR that provides a rapid route for the preparation of a-aminoacyl amide derivatives. The Ugi 4 component condensation of an amine, oxo compound, carboxylic acid and an isocyanide is the most documented
Aldehydes - Types & Structure
Technical article regarding Aldehydes - Types & Structure
Periodic Table of the Elements
Download the Periodic Table of the Elements with names, atomic mass and number in printable .pdf and image format. Use the periodic table chart by element names in alphabetical order for quick research, reference and lab use. From MilliporeSigma.
Friedel–Crafts Acylation
The Friedel–Crafts acylation is the reaction of an arene with acyl chlorides or anhydrides using a strong Lewis acid catalyst. This reaction proceeds via electrophilic aromatic substitution to form monoacylated products.
Protected Carbohydrate Building Blocks for More Efficient Syntheses
Carbohydrates and their biologically active glycoconjugate analogs are emerging as an important class of biomolecules.
Heck Reaction
The Heck reaction is the palladium catalyzed cross-coupling reaction between alkenes and aryl or vinyl halides (or triflates) to afford substituted alkenes.
1-hydrosilatrane
As a versatile hydride reagent, 1-hydrosilatrane can be used in reduction reactions to synthesize alcohols, amines, their chiral counterparts, and esters from aldehydes/ketones.
VSEPR Chart | Valence Shell Electron Pair Repulsion Theory
Use our handy VSEPR chart to find the 3-D geometric VSEPR shapes of molecules and ions. Learn about VSEPR theory and shapes like trigonal planar or square pyramidal. VSEPR stands for valence shell electron pair repulsion.
Spirocyclic Building Blocks for Scaffold Assembly
Spirocyclic modules containing four-membered rings are currently of growing interest to discovery chemists.
Synthia™ Organic Retrosynthesis Software - Resources
Learn more about Synthia™ Organic Retrosynthesis Software and view a list of publications
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