CN
DCX
doublecortin
别名:
DBCN, DC, LISX, SCLH, XLIS
物种:
Human DCX (1641), Mouse Dcx (13193), Rat Dcx (84394), sheep DCX (101109861), naked mole-rat Dcx (101711611), domestic guinea pig Dcx (100713827), chicken DCX (374242), domestic cat DCX (494212), cow DCX (787968), Horse DCX (100058909)
UniProtKB ID:
基因ID:
- Human(1641) Summary: This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
- Mouse(13193) doublecortin
- Rat(84394) doublecortin
- sheep(101109861) doublecortin
- naked mole-rat(101711611) doublecortin
- domestic guinea pig(100713827) doublecortin
- chicken(374242) doublecortin
- domestic cat(494212) doublecortin
- cow(787968) doublecortin
- Horse(100058909) doublecortin
- dog(612950) doublecortin
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
抗-DCX抗体，克隆2G5, clone 2G5, from mouse,
物种反应性
human, mouse
应用
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-DCX (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-DCX antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Dcx antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-DCX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
esiRNA
货号
说明
物种