45480
麦角甾醇
≥95.0% (HPLC)
别名:
(3β)-麦角-5,7,22-三烯甘油-3-醇, 3β-羟基-5,7,22-麦角三烯, 维生素原 D2
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经验公式（希尔记法）:
C28H44O
化学文摘社编号:
分子量:
396.65
UNSPSC Code:
12352211
NACRES:
NA.79
PubChem Substance ID:
EC Number:
200-352-7
Beilstein/REAXYS Number:
2338604
MDL number:
InChI key
DNVPQKQSNYMLRS-APGDWVJJSA-N
InChI
1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
SMILES string
[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
biological source
plant
assay
≥95.0% (HPLC)
form
powder or crystals
optical activity
[α]20/D −120±10°, c = 1% in chloroform
impurities
~3% water
color
white to faint yellow
mp
156-158 °C (lit.), 160-163 °C
functional group
hydroxyl
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
麦角甾醇是维生素 D2 的生物前体，存在于真菌和一些原生生物如锥虫的细胞膜中。麦角甾醇可用于抗真菌药物如两性霉素 B 及其类似物的功能研究以及各种真菌中麦角甾醇生物合成途径的研究。
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Rapid resolution liquid chromatography/tandem multi-stage mass spectrometry (RRLC-MS(n)) and rapid resolution liquid chromatography/tandem mass spectrometry (RRLC/MS/MS) methods were developed for the identification and quantification of ergosterol and its metabolites from rat plasma, urine and faeces. Two metabolites (ERG1 and ERG2)
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Three extraction methods were sequentially combined to obtain fractions from Lentinula edodes (shiitake mushrooms) containing bioactive compounds against cardiovascular diseases (CVDs). Fruiting bodies were first extracted with plain water, obtained residue was then submitted to supercritical fluid extraction (SFE) and
Daniel S Palacios et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(17), 6733-6738 (2011-03-04)
Amphotericin B is the archetype for small molecules that form transmembrane ion channels. However, despite extensive study for more than five decades, even the most basic features of this channel structure and its contributions to the antifungal activities of this
Michael Zick et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(18), E2290-E2297 (2015-04-23)
Sec17 [soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein; α-SNAP] and Sec18 (NSF) perform ATP-dependent disassembly of cis-SNARE complexes, liberating SNAREs for subsequent assembly of trans-complexes for fusion. A mutant of Sec17, with limited ability to stimulate Sec18, still strongly enhanced fusion
Shu-Jing Wu et al.
The American journal of Chinese medicine, 41(1), 131-144 (2013-01-23)
Grifola frondosa (GF), a high value medicinal mushroom in China and Japan, is popularly consumed as traditional medicines and health foods, especially for enhancing immune functions. In this study, our aim was to examine the immunomodulatory activities of GF and
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