Process intensification has become a strategic focus aimed at efficiently increasing productivity. A key example of this in upstream is utilizing perfusion within the seed train, yielding a reduction in process time and/or increase in manufacturing capacity without increasing volume capacity. With recent advances in cell retention technologies, coupled with advancements in cell line and media development, perfusion processes are becoming a more viable solution. We will present a case study utilizing our novel perfusion filter and controller along with a newly developed expansion medium, demonstrating an ideal solution to intensify upstream processing.
In this webinar, you will learn about:
- Considerations for a scalable cell retention device for perfusion applications
- A case study demonstrating capabilities of novel perfusion filter and controller for intensified upstream processing
Speakers
Alison Dupont
Merck
Senior Applications Engineer, Single-Use and Integrated Systems
Alison Dupont is a senior applications engineer within the single-use and integrated systems group. She holds an M.S. in chemical engineering. Her current role is to be the “customer ambassador” on active product development projects within the single-use and integrated system product pipeline. Alison has more than 14 years of experience in MAb processing in both upstream and downstream, with a focus on intensified processing.
Allyson Fournier
Merck
Application Engineer, Single-Use and Integrated Systems R&D
Allyson Fournier has been highly involved with the development of a line of novel cell retention filters and systems to be used on a perfusion bioreactor. She supports the single-use and integrated systems R&D team to provide application work for the launch of new products. Allyson brings a background in chemical engineering and biotechnology.
Pharma and biopharma manufacturing
- Cell Line Development
Duration:59min
Language:English
Session 1:presented January 23, 2020
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