CBX3
chromobox homolog 3
Synonyms:
HECH, HP1-GAMMA, HP1Hs-gamma
Species:
Human CBX3 (11335), Mouse Cbx3 (12417), Rat Cbx3 (297093), naked mole-rat Cbx3 (101714000), domestic guinea pig Cbx3 (100714020), sheep CBX3 (101106931), chicken CBX3 (395355), dog CBX3 (482015), cow CBX3 (539788), domestic cat CBX3 (101099363)
UniProtKB ID:
Gene ID:
- Human(11335) Summary: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
- Mouse(12417) chromobox 3
- Rat(297093) chromobox homolog 3
- naked mole-rat(101714000) chromobox homolog 3
- domestic guinea pig(100714020) chromobox homolog 3
- sheep(101106931) chromobox homolog 3
- chicken(395355) chromobox homolog 3
- dog(482015) chromobox homolog 3
- cow(539788) chromobox homolog 3
- domestic cat(101099363) chromobox homolog 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CBX3 antibody produced in mouse, clone 1G12-1D9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Phospho-CBX3-S83 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-HP1γ Antibody, clone 14D3.1, clone 14D3.1, from mouse,
Species Reactivity
human, mouse, nonhuman primates, rat
Application
immunocytochemistry
western blot
western blot
Anti-phospho-HP1 γ (Ser83) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-CBX3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species