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Merck
CN

S9009

Sar-Pro-Arg p-nitroanilide dihydrochloride

thrombin substrate, ≥97% (HPLC), powder

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About This Item

Empirical Formula (Hill Notation):
C20H30N8O5 · 2HCl
CAS Number:
Molecular Weight:
535.42
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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Product Name

Sar-Pro-Arg p-nitroanilide dihydrochloride, thrombin substrate

Quality Level

assay

≥97% (HPLC)

form

powder

solubility

water: 25 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

Cl.CNCC(=O)N1CCCC1C(=O)NC(CCCNC(N)=N)C(=O)Nc2ccc(cc2)N(=O)=O

InChI

1S/C20H30N8O5.ClH/c1-23-12-17(29)27-11-3-5-16(27)19(31)26-15(4-2-10-24-20(21)22)18(30)25-13-6-8-14(9-7-13)28(32)33;/h6-9,15-16,23H,2-5,10-12H2,1H3,(H,25,30)(H,26,31)(H4,21,22,24);1H

InChI key

KMSNYOSWLIQVAN-UHFFFAOYSA-N

General description

Chromogenic substrate for thrombin.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Protocols

凝血酶是一种内溶性丝氨酸蛋白酶,可选择性裂解纤维蛋白原的精氨酸-甘氨酸键,从而形成纤维蛋白并释放纤维蛋白肽A和B。

Thrombin is an endolytic serine protease that selectively cleaves the Arg–Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.