T3068
Thrombin generation chromogenic substrate
≥90% (HPLC), solid
Synonym(s):
β-Ala-Gly-Arg-p-nitroanilide diacetate
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C21H34N8O9
Molecular Weight:
542.54
UNSPSC Code:
12352204
NACRES:
NA.32
MDL number:
Form:
solid
Assay:
≥90% (HPLC)
Biological source:
synthetic (organic)
biological source
synthetic (organic)
Quality Level
assay
≥90% (HPLC)
form
solid
technique(s)
activity assay: suitable
storage temp.
2-8°C
SMILES string
[N+](=O)([O-])c1ccc(cc1)NC(=O)[C@@H](NC(=O)CNC(=O)CCN)CCCNC(=N)N.OC(=O)C.OC(=O)C
InChI key
PBMJNSQKWBTVOL-GXKRWWSZSA-N
Application
Thrombin generation chromogenic substrate can be used for chromogenic assay developed through aptamer affinity capture and a subsequent enzyme reaction for detecting the thrombin in dilute human serum.
Biochem/physiol Actions
Thrombin generation chromogenic substrate also known as beta-Ala-Gly-Arg para-nitroanilide, is proteolytically cleaved by human thrombin and produces beta-Ala-Gly-Arg and p-nitroanilide. The release of p-nitroanilide is quatified for assesing the anti-thrombin activity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Protocols
凝血酶是一种内溶性丝氨酸蛋白酶，可选择性裂解纤维蛋白原的精氨酸-甘氨酸键，从而形成纤维蛋白并释放纤维蛋白肽A和B。
Thrombin is an endolytic serine protease that selectively cleaves the Arg–Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.