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1.00886

Ethyl 4-hydroxybenzoate sodium salt

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

Synonym(s):

Ethyl 4-hydroxybenzoate sodium salt, p-Hydroxybenzoic acid ethyl ester sodium salt, Ethylparaben sodium salt

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About This Item

Empirical Formula (Hill Notation):
C9H9NaO3
CAS Number:
35285-68-8
Molecular Weight:
188.16
MDL number:
MFCD00016475
UNSPSC Code:
12352108
EC Index Number:
252-487-6
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Quality Level

500

agency

BP, NF, Ph. Eur.

product line

EMPROVE® ESSENTIAL

form

solid

pH

10 (20 °C, 1 g/L in H2O)

bp

297 °C/1013 hPa (free ester,decomposition)

mp

>115 °C (free ester)

transition temp

flash point 121 °C

solubility

1000 g/L

application(s)

liquid formulation
ophthalmics
pharmaceutical

storage temp.

15-25°C

SMILES string

[Na+].[O-]c1ccc(cc1)C(=O)OCC

InChI

1S/C9H10O3.Na/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6,10H,2H2,1H3;/q;+1/p-1

InChI key

QYNMSPKSYXPZHG-UHFFFAOYSA-M

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to the US EPA′s Federal Insecticide Fungicide and Rodenticide Act, the European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR), and others.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

249.8 °F

flash_point_c

121 °C

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
100886500004022536011493