N2165
NKY80
≥98% (HPLC)
Synonym(s):
2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone
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About This Item
Empirical Formula (Hill Notation):
C12H11N3O2
CAS Number:
Molecular Weight:
229.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
assay
≥98% (HPLC)
form
powder
color
off-white to light brown
solubility
DMSO: ≥30 mg/mL
storage temp.
2-8°C
SMILES string
Nc1ncc2C(=O)CC(Cc2n1)c3ccco3
InChI
1S/C12H11N3O2/c13-12-14-6-8-9(15-12)4-7(5-10(8)16)11-2-1-3-17-11/h1-3,6-7H,4-5H2,(H2,13,14,15)
InChI key
SOJUSNIBPPMLCC-UHFFFAOYSA-N
Biochem/physiol Actions
NKY80 is a selective adenylyl cyclase-V inhibitor with greater than 200-fold selectivity for type V over the type II isoform.
NKY80 is a selective adenylyl cyclase-V inhibitor.
Features and Benefits
This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Articles
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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