SML0060
NB001
≥98% (HPLC)
Synonym(s):
5-[[2-(6-Amino-9H-purin-9-yl)ethyl]amino]-1-pentanol; HTS 09836
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C12H20N6O
CAS Number:
Molecular Weight:
264.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to tan
solubility
H2O: ≥24 mg/mL
storage temp.
−20°C
SMILES string
Nc1ncnc2n(CCNCCCCCO)cnc12
InChI
1S/C12H20N6O/c13-11-10-12(16-8-15-11)18(9-17-10)6-5-14-4-2-1-3-7-19/h8-9,14,19H,1-7H2,(H2,13,15,16)
InChI key
CVPTTZZCRDVGSU-UHFFFAOYSA-N
Application
NB001 may be used in adenylyl cyclase 1-mediated cell signaling studies.
Biochem/physiol Actions
NB001, originally believed to be a selective inhibitor of adenylyl cyclase 1 (AC1), new evidence suggests NB001 does not interact with AC1 directly. NB001 may reduce cAMP accumulation in cells through an unknown mechanism that is dependent on AC1.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Articles
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.