569755

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Showing 1-11 of 11 results for "569755" within Papers

Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors.

Yamashita DS, et al.

Journal of Medicinal Chemistry, 49(5), 1597-1612 (2006)

Ring-opening metathesis/oxy-cope rearrangement: a new strategy for the synthesis of bicyclic medium ring-containing compounds.

Brian H White et al.

Journal of the American Chemical Society, 125(48), 14901-14904 (2003-12-04)

Ring-opening/ring-closing metathesis on cyclobutene-containing substrates with angular oxygen functionality provides a stereospecific introduction of 1,5-bis-dienes required for an anion-accelerated oxy-Cope rearrangement. The reaction sequence offers generally a stereocontrolled preparation of a variety of medium ring-containing bicyclic ring systems, while rearrangement

The development of L2X2Ru=CHR olefin metathesis catalysts: an organometallic success story.

T M Trnka et al.

Accounts of chemical research, 34(1), 18-29 (2001-02-15)

In recent years, the olefin metathesis reaction has attracted widespread attention as a versatile carbon-carbon bond-forming method. Many new applications have become possible because of major advances in catalyst design. State-of-the-art ruthenium catalysts are not only highly active but also

Ruthenium catalysed cross metathesis with fluorinated olefins.

S Imhof et al.

Chemical communications (Cambridge, England), (17), 1692-1693 (2002-09-21)

The E-selective cross metathesis (CM) of fluorinated olefins with various functionalised alkenes in good to excellent yields is reported.

Schrodi, Y.; Pederson, R. L.

Aldrichimica Acta, 45-45 (2007)

Sequential catalysis: a metathesis/dihydroxylation sequence.

Samuel Beligny et al.

Angewandte Chemie (International ed. in English), 45(12), 1900-1903 (2006-02-14)

Vougioukalakis, G. C.; Grubbs, R. H.

Chemical Reviews, 1746-1746 (2010)

Highly efficient ruthenium catalysts for the formation of tetrasubstituted olefins via ring-closing metathesis.

Ian C Stewart et al.

Organic letters, 9(8), 1589-1592 (2007-03-24)

[reaction: see text] A series of ruthenium-based metathesis catalysts with N-heterocyclic carbene (NHC) ligands have been prepared in which the N-aryl groups have been changed from mesityl to mono-ortho-substituted phenyl (e.g., tolyl). These new catalysts offer an exceptional increase in

Schuster, M.; Blechert, S.

Angewandte Chemie (International Edition in English), 2036-2036 (1997)

Low catalyst loadings in olefin metathesis: synthesis of nitrogen heterocycles by ring-closing metathesis.

Kevin M Kuhn et al.

Organic letters, 12(5), 984-987 (2010-02-10)

A series of ruthenium catalysts have been screened under ring-closing metathesis (RCM) conditions to produce five-, six-, and seven-membered carbamate-protected cyclic amines. Many of these catalysts demonstrated excellent RCM activity and yields with as low as 500 ppm catalyst loadings.

Synthesis of the HCV protease inhibitor Vaniprevir (MK-7009) using ring-closing metathesis strategy.

Kong J, et al.

The Journal of Organic Chemistry, 77(8), 3820-3828 (2012)

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