Jennifer Pfizenmaier et al.
Biotechnology progress, 31(5), 1212-1216 (2015-07-07)
A variety of approaches has been published to enhance specific productivity (qp) of recombinant Chinese hamster ovary (CHO) cells. Changes in culture conditions, e. g. temperature shifts, sodium butyrate treatment and hyperosmolality, were shown to improve qp . To contribute