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Showing 1-30 of 40 results for "S9751" within Papers
Rentsenkhand Sambuu et al.
The Journal of reproduction and development, 57(2), 303-306 (2010-12-09)
Zearalenone (ZEN) and its metabolites are important nonsteroidal estrogenic mycotoxins that cause reproductive disorders in domestic animals, especially pigs. We aimed to simultaneously detect ZEN and its metabolites á-zearalenol (α-ZOL) and β-zearalenol (β-ZOL) in porcine follicular fluid (FF) by liquid
Jean-Marie Volland et al.
Microscopy research and technique, 75(10), 1353-1360 (2012-05-26)
Strombus gigas and Strombus pugilis are threatened species and aquaculture represents a good alternative solution to the fishing. In this study, we highlighted the intracellular digestion process in the digestive gland of two Strombidae species, S. gigas and Strombuspugilis, by
Lisanne D'Andrea-Winslow et al.
Integrative zoology, 7(1), 61-73 (2012-03-13)
Sea urchin petalloid coelomocytes effectuate the clotting pathway by undergoing a rapid and dynamic cellular transformation that leads to cellular adhesion and wounds closure. We have identified high levels of activity of arylsulfatase (Ars) associated with coelomocytes of the sea
Yishuo Wu et al.
International urology and nephrology, 47(6), 965-970 (2015-05-15)
Genistein is one of the main soy isoflavones in our daily diet. There were studies proving that high-dietary intake of genistein may relate to the low morbidity and mortality of prostate cancer (PCa) in the Asian population. Since there were
Jakub Kopycki et al.
Biotechnology letters, 33(5), 1039-1046 (2011-01-27)
Thiohydroximates comprise a diverse class of compounds important in both biological and industrial chemistry. Their syntheses are generally limited to simple alkyl and aryl compounds with few stereocenters and a narrow range of functional groups. We hypothesized that sequential action
Małgorzata Dżugan et al.
Acta veterinaria Hungarica, 59(3), 337-347 (2011-07-06)
The aim of the study was to determine the toxicity of cadmium ions in chick embryos, using plasma hydrolytic enzyme as its biomarker. Hatching eggs (n = 300) from Ross 308 broilers were incubated under standard conditions. On day 4
Estatira Sepehr et al.
Journal of pharmaceutical and biomedical analysis, 71, 119-126 (2012-09-18)
Estrogen receptor (ER) subtype specific agonists, diarylpropionitrile (DPN) for ERβ and propylpyrazoletriol (PPT) for ERα, are pharmacological probes used frequently to define mechanisms for estrogen actions in vitro and in vivo. Quantitative analytical methodology was developed and validated for DPN
Haruna Takagi et al.
Journal of biochemistry, 151(1), 75-87 (2011-09-21)
The Ars insulator is a boundary element identified in the upstream region of the arylsulfatase (HpArs) gene in the sea urchin, Hemicentrotus pulcherrimus, and possesses the ability to both block enhancer-promoter communications and protect transgenes from silent chromatin. To understand
Jinghui Luo et al.
FEBS letters, 586(11), 1622-1630 (2012-06-08)
In recent years, it has become increasingly clear that many enzymes are catalytically "promiscuous". This can provide a springboard for protein evolution, allowing enzymes to acquire novel functionality without compromising their native activities. We present here a detailed study of
Glucosamine-6-sulfamate analogues of heparan sulfate as inhibitors of endosulfatases.
Mathias Schelwies et al.
Chembiochem : a European journal of chemical biology, 11(17), 2393-2397 (2010-10-26)
Christopher L King et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(50), 20113-20118 (2011-11-30)
Plasmodium vivax (Pv) is a major cause of human malaria and is increasing in public health importance compared with falciparum malaria. Pv is unique among human malarias in that invasion of erythrocytes is almost solely dependent on the red cell's
David R Edwards et al.
The Journal of organic chemistry, 77(9), 4450-4453 (2012-04-11)
The hydrolysis of N-methyl O-phenyl sulfamate (1) has been studied as a model for steroid sulfatase inhibitors such as Coumate, 667 Coumate, and EMATE. At neutral pH, simulating physiological conditions, hydrolysis of 1 involves an intramolecular proton transfer from nitrogen
Yaser A Mostafa et al.
Bioorganic & medicinal chemistry, 20(4), 1535-1544 (2012-01-24)
Steroid sulfatase (STS) catalyzes the desulfation of biologically inactive sulfated steroids to yield biologically active desulfated steroids and is currently being examined as a target for therapeutic intervention for the treatment of breast and other steroid-dependent cancers. Here we report
Priyanka Chaudhary et al.
Environmental monitoring and assessment, 184(2), 1145-1156 (2011-04-21)
The present study is aimed at analysing and comparing different soil enzymes in soil samples of native contaminated sites of a Mathura refinery and adjoining agricultural land. Enzyme activities are considered as indicators of soil quality and changes in biogeochemical
Beat B Fischer et al.
BMC plant biology, 10, 279-279 (2010-12-21)
When photosynthetic organisms are exposed to harsh environmental conditions such as high light intensities or cold stress, the production of reactive oxygen species like singlet oxygen is stimulated in the chloroplast. In Chlamydomonas reinhardtii singlet oxygen was shown to act
Jinghui Luo et al.
Proteins, 80(4), 1211-1226 (2012-01-26)
Pseudomonas aeruginosa arylsulfatase (PAS) is a bacterial sulfatase capable of hydrolyzing a range of sulfate esters. Recently, it has been demonstrated to also show very high proficiency for phosphate ester hydrolysis. Such proficient catalytic promiscuity is significant, as promiscuity has
Marina Pfalz et al.
The Plant cell, 21(3), 985-999 (2009-03-19)
Glucosinolates are defensive secondary compounds that display large structural diversity in Arabidopsis thaliana and related plants. Much attention has been paid to variation in the biosynthesis of Met-derived aliphatic glucosinolates and its ecological consequences, but little is known about the
The activation of an arysulphatase from ox liver by chloride and other anions.
E C WEBB et al.
The Biochemical journal, 73, 7-15 (1959-09-01)
Abigail M Tokheim et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 18(5), 537-540 (2005-12-08)
Often used to remove sulfate groups from carbohydrates, the regulatory properties of the aryl sulfatase from Helix pomatia remain little characterized. As many hydrolytic enzymes utilize exogenous metal ions in catalysis, the effect of various divalent metal ions on the
Adam M Wightwick et al.
Environmental science and pollution research international, 20(3), 1574-1585 (2012-08-15)
The use of copper-based fungicides leads to an accumulation of copper (Cu) in vineyard soils, potentially causing adverse effects to the microbial function and fertility of the soil. This study used a soil microcosm approach to assess the effects of
Suzanna M Zick et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17(8), 1930-1936 (2008-08-19)
Ginger shows promising anticancer properties. No research has examined the pharmacokinetics of the ginger constituents 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol in humans. We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of these
G Pelsy et al.
Biotechnology and bioengineering, 25(4), 919-928 (1983-04-01)
It has been found that sulfatase from Helix pomatia hydrolyzes beta-naphthyl sulfate much faster than alpha-naphthyl sulfate; e.g., at pH 7.8, while the former is readily hydrolyzed, the latter undergoes no appreciable hydrolysis. Kinetic investigations of both enzymatic and acid
Alessandra Trojani et al.
Cancer biomarkers : section A of Disease markers, 11(1), 15-28 (2011-01-01)
Several studies demonstrated IGVH mutational status and ZAP70 expression as the most relevant prognostic markers in Chronic Lymphocytic Leukemia (CLL), suggesting the separation of two patient subgroups: with good mutated ZAP70 negative (MTZAP70(-) and poor unmutated ZAP70 positive (UMZAP70(+)) prognosis.
Kenneth Dr Setchell et al.
The American journal of clinical nutrition, 90(4), 1029-1037 (2009-08-28)
The nonsteroidal estrogen equol occurs as diastereoisomers, S-(-)equol and R-(+)equol, both of which have significant biological actions. S-(-)equol, the naturally occurring enantiomer produced by 20-30% of adults consuming soy foods, has selective affinity for estrogen receptor-beta, whereas both enantiomers modulate
Youssef Ouni et al.
International journal of phytoremediation, 15(2), 188-197 (2013-03-16)
In the present work, we studied the effectiveness of the predominant halophytes of Soliman sabkha (Tecticornia indica and Suaeda fruticosa) to promote soil biological activities and ecosystem productivity. Soil Arylsulphatese ARY, beta-glucosidase beta-GLU, phosphatase PHO, invertase INV, urease URE, and
A Almási et al.
Acta physiologica Hungarica, 100(4), 478-488 (2013-09-10)
The aim of these experiments was the investigation of the correlation between the metabolic enzyme activities and the intestinal and hepatic excretion of p-nitrophenol (PNP) and its metabolites (PNP-glucuronide: PNP-G and PNP-sulfate: PNP-S) in the same group of rats (n
Christiane Kehrer et al.
Developmental medicine and child neurology, 53(9), 850-855 (2011-06-29)
Motor deterioration is a key feature in metachromatic leukodystrophy (MLD). The lack of data about its natural course impedes evaluation of therapeutic interventions. This study aimed to provide data about motor decline in MLD. Fifty-nine patients (27 males, 32 females)
S Saha et al.
Pharmacological research, 65(6), 592-602 (2012-03-01)
Epicatechin is a widely consumed dietary flavonoid and there is substantial evidence that it contributes to the health benefits reported for flavanol-rich cocoa products including dark chocolate. Numerous reports have described the appearance of epicatechin and epicatechin phase-2 conjugates (sulfates
Elena Marie Wiegmann et al.
The Journal of biological chemistry, 288(42), 30019-30028 (2013-08-30)
The human sulfatase family has 17 members, 13 of which have been characterized biochemically. These enzymes specifically hydrolyze sulfate esters in glycosaminoglycans, sulfolipids, or steroid sulfates, thereby playing key roles in cellular degradation, cell signaling, and hormone regulation. The loss
Björn Kowalewski et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(26), 10310-10315 (2012-06-13)
Deficiency of glycosaminoglycan (GAG) degradation causes a subclass of lysosomal storage disorders called mucopolysaccharidoses (MPSs), many of which present with severe neuropathology. Critical steps in the degradation of the GAG heparan sulfate remain enigmatic. Here we show that the lysosomal
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