105937
3,4,4′-三氯二苯脲
99%
别名:
1-(4-氯苯基)-3-(3,4-二氯苯基)脲, TCC, 三氯卡班
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关于此项目
线性分子式:
Cl2C6H3NHCONHC6H4Cl
化学文摘社编号:
分子量:
315.58
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
99%
Form:
solid
agency
EPA 1694
Quality Level
vapor pressure
<0.1 mmHg ( 25 °C)
assay
99%
form
solid
mp
254-256 °C (lit.)
solubility
methanol: soluble
application(s)
environmental
functional group
amine, chloro
SMILES string
Clc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1
InChI
1S/C13H9Cl3N2O/c14-8-1-3-9(4-2-8)17-13(19)18-10-5-6-11(15)12(16)7-10/h1-7H,(H2,17,18,19)
InChI key
ICUTUKXCWQYESQ-UHFFFAOYSA-N
Gene Information
human ... EPHX2(2053)
mouse ... Ephx2(13850)
General description
3,4,4′-三氯卡巴腈 (TCC) 在肥皂、化妆品和其他个人护理用品中用作抑菌剂和抗菌剂。TCC 是一种有毒、持久性和潜在生物累积性的多氯联苯类芳香族尿素农药。
Application
采用 3,4,4′-三氯卡巴腈建立了一种灵敏分析方法，以通过同位素稀释在线固相萃取-高效液相色谱串联质谱法测定母乳中的三氯卡班和环境酚类物质。为研究美国水资源中三氯卡班和三氯生的共生关系，采用 3,4,4′-三氯卡比林进行了定量构效关系 (QSAR) 分析。
Biochem/physiol Actions
3,4,4'-三氯卡巴尼对哺乳动物生殖有干扰，可引起人体高铁血红蛋白血症。
Disclaimer
本品不可用作全球生物杀灭剂法规监管的生物杀灭剂，包括但不限于：美国联邦杀虫剂、杀菌剂和灭鼠剂法(US EPA′s Federal Insecticide Fungicide and Rodenticide Act)、欧盟生物杀灭剂法规(European Biocidal Products Regulation)、加拿大虫害管理监管机构(Canada’s Pest Management Regulatory Agency)、土耳其生物杀灭剂法规(Turkey’s Biocidal Products Regulation)、韩国生物杀灭剂法(Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR))等。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
Rong Chu et al.
Oncotarget, 7(48), 78958-78970 (2016-10-16)
Microtubule targeting agents (MTAs) characteristically promote phosphorylation and degradation of Mcl-1, and this represents a critical pro-apoptotic signal in mitotic death. While several phosphorylation sites and kinases have been implicated in mitotic arrest-induced Mcl-1 phosphorylation, a comprehensive biochemical analysis has
Biodegradation of 3, 4, 4'-trichlorocarbanilide, TCC?, in sewage and activated sludge.
Gledhill WE.
Water Research, 9(7), 649-654 (1975)
Jian-Liang Zhao et al.
Water research, 47(1), 395-405 (2012-11-07)
Triclosan (TCS) and triclocarban (TCC) are two commonly used personal care products. They may enter into aquatic environments after consumption and pose potential risks to aquatic organisms. We investigated the occurrence and fate of TCS and TCC in five large
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 105937-100G | 04061838673299 |
| 105937-5G | 04061838673305 |