160210
氯甲酸对硝基苯酯
96%, for peptide synthesis
别名:
氯甲酸-4-硝基苯酯
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关于此项目
线性分子式:
ClCO2C6H4NO2
化学文摘社编号:
分子量:
201.56
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
EC Number:
231-706-9
MDL number:
Beilstein/REAXYS Number:
518127
产品名称
氯甲酸对硝基苯酯, 96%
Quality Level
assay
96%
form
powder
reaction suitability
reaction type: Carbonylations
bp
159-162 °C/19 mmHg (lit.)
mp
77-79 °C (lit.)
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
[O-][N+](=O)c1ccc(OC(Cl)=O)cc1
InChI
1S/C7H4ClNO4/c8-7(10)13-6-3-1-5(2-4-6)9(11)12/h1-4H
InChI key
NXLNNXIXOYSCMB-UHFFFAOYSA-N
General description
4-硝基苯基氯甲酸酯，也称为氯甲酸对硝基苯酯，可作为偶联剂合成尿素、甲酸酯和碳酸酯。也用作固相肽合成(SPPS)构件，用于获得不同的侧链官能团。
Application
4-硝基苯基氯甲酸酯用于：
- 作为偶联剂连接药物分子与聚轮烷载体
- 作为活化酯试剂，使多肽共价偶联大分子单体，例如(聚(乙二醇)延胡索酸酯)低聚物(OPF)
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
>230.0 °F
flash_point_c
> 110 °C
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Macromolecular Rapid Communications, 15, 697-697 (1994)
Zhuojun Gu et al.
Drug development and industrial pharmacy, 41(5), 812-818 (2014-04-22)
Polyamidoamine (PAMAM) dendrimers have attracted lots of interest as drug carriers. And little study about whether pluronic-attached PAMAM dendrimers could be potential drug delivery systems has been carried on. Pluronic F127 (PF127) attached PAMAM dendrimers were designed as novel drug
Novel and Efficient Synthesis of 4-Substituted-1, 2, 4-triazolidine-3, 5-diones from Anilines.
Mallakpour S and Rafiee Z
Synthetic Communications, 37(11), 1927-1934 (2007)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 160210-100G | 04061833554371 |
| 160210-5G | 04061838745347 |
| 160210-25G | 04061838745330 |