Merck
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文件

202444

Sigma-Aldrich

聚（乙二醇）

average Mn 3,350, powder

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别名:
PEG
线性分子式:
H(OCH2CH2)nOH
CAS号:
25322-68-3
MDL编号:
MFCD00081839
PubChem化学物质编号:
24852064

形式

powder

分子量

average Mn 3,350

pH值（酸碱度）

4.5-7.5

粘度

90 cSt(210 °F) (99 °C)(lit.)

mp

54-58 °C (lit.)

密度

1.204 g/mL at 25 °C

Ω端

hydroxyl

α端

hydroxyl

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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相关类别

一般描述

聚乙二醇(PEG)是一种人造生物相容性惰性聚合物，由醚氧(-CH2-CH2-O-)重复单元构成。可通过氧乙烯的阴离子聚合反应制得。因具有非免疫原性和高水溶性，广泛用于生物和医学领域。

应用

聚乙二醇可用于修饰磁铁矿纳米粒子。在磁核上涂覆PEG外壳可使纳米粒子在保持磁性的前提下具备良好的稳定性。

PEG可用于修饰光催化TiO2纳米粉末，用于制造自清洁涂料。PEG涂覆的TiO2纳米粉末可通过温和条件制备，具有优异的胶体稳定性。

可用作交联剂，制备基于聚N-异丙基丙烯酰胺的热敏型可注射水凝胶。引入PEG提高了水凝胶的化学和机械性能，防止水凝胶在溶胀介质中溶解。这种水凝胶由于生物相容性和生物可降解性，广泛用于生物医学领域。

特点和优势

  • 结构柔性高
  • 生物相容性
  • 水化能力高
  • 无任何空间位阻

其他说明

分子量：Mn 3,015-3,685

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Grant A Robinson et al.
Journal of neuroscience research, 94(7), 636-644 (2016-03-21)
Functional recovery following a peripheral nerve injury is made easier when regenerating axons correctly reinnervate their original targets. Polyethylene glycol (PEG) has recently been used in attempts to fuse severed peripheral axons during suture-based repair, but an analysis of target
Erinna F Lee et al.
Autophagy, 15(5), 785-795 (2019-01-11)
BECN1/Beclin 1 is a critical protein in the initiation of autophagosome formation. Recent studies have shown that phosphorylation of BECN1 by STK4/MST1 at threonine 108 (T108) within its BH3 domain blocks macroautophagy/autophagy by increasing BECN1 affinity for its negative regulators
Yixu Wang et al.
mSphere, 4(3) (2019-05-31)
Sporisorium scitamineum is the fungal pathogen causing severe sugarcane smut disease that leads to massive economic losses globally. S. scitamineum invades host cane by dikaryotic hyphae, formed after sexual mating of two haploid sporidia of opposite mating type. Therefore, mating/filamentation
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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