Quality Level
reaction suitability
reaction type: Grignard Reaction
packaging
Sure/Seal™ of
concentration
2.0 M in THF
density
0.975 g/mL at 25 °C
SMILES string
CC(C)[Mg]Cl
InChI
1S/C3H7.ClH.Mg/c1-3-2;;/h3H,1-2H3;1H;/q;;+1/p-1
InChI key
GPIBKUJXKCEZOH-UHFFFAOYSA-M
General description
异丙基氯化镁是一种高反应活性的有机镁卤化物,由金属镁和异丙基氯 反应而成。它可用于格氏反应以生成新的碳碳键。
Application
异丙基氯化镁溶液(2.0M,溶于THF)可作为合成以下物质的试剂:
- 在甲酸乙酯甲酰化剂存在的情况下,通过5-取代的1,2,3-三碘苯的区域选择性金属-碘交换反应制备2,6-二碘苯甲醛衍生物。
- 由芳基和杂芳基溴化物通过形成相应的格氏试剂制备芳烃和杂芳烃磺酰胺。
- 以溴/碘吡啶处理,然后用氯化硒SeCl2处理制备的对称吡啶基单硒化物。
Packaging
建议将25 mL Sure/Seal™ 瓶作为一次性瓶使用。 反复穿刺可能会导致产品性能下降。
Legal Information
Sure/Seal is a trademark of Sigma-Aldrich Co. LLC
Still not finding the right product?
Explore all of our products under 异丙基氯化镁 溶液
signalword
Danger
target_organs
Central nervous system, Respiratory system
supp_hazards
存储类别
4.3 - Hazardous materials which set free flammable gases upon contact with water
wgk
WGK 1
flash_point_f
1.4 °F - closed cup
flash_point_c
-17 °C - closed cup
Hazard Classifications
Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react. 1
法规信息
危险化学品
此项目有
商品
Substantial progress has been made in magnesium–halogen exchange reactions used for the preparation of functionalized Grignard reagents containing sensitive moieties such as ester or cyano groups.
相关内容
Baran Reagents - FAQ
Oleg V Larionov et al.
Organic letters, 16(3), 864-867 (2014-01-15)
A one-step transformation of heterocyclic N-oxides to 2-alkyl-, aryl-, and alkenyl-substituted N-heterocycles is described. The success of this broad-scope methodology hinges on the combination of copper catalysis and activation by lithium fluoride or magnesium chloride. The utility of this method
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 230111-2.5L | 04061838125774 |
| 230111-4X100ML | 04061838782359 |
| 230111-800ML | 04061838782373 |
| 230111-100ML | 04061838782342 |
| 230111-4X25ML | 04061838782366 |
| 230111-PZ | 04061826597286 |



