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Merck
CN

391913

(R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸

98%

别名:

(2R)-3,4-二氢-6-羟基-2,5,7,8-四甲基-2H-1-苯并吡喃-2-甲酸, (R)-Trolox

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关于此项目

经验公式(希尔记法):
C14H18O4
化学文摘社编号:
分子量:
250.29
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
98%
Form:
solid
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assay

98%

form

solid

optical activity

[α]27/D +65°, c = 1.2 in ethanol

mp

162 °C (dec.) (lit.)

functional group

carboxylic acid

SMILES string

Cc1c(C)c2O[C@](C)(CCc2c(C)c1O)C(O)=O

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)/t14-/m1/s1

InChI key

GLEVLJDDWXEYCO-CQSZACIVSA-N

General description

( R )-(+)-6-羟基-2,5,7,8-四甲基色-2-羧酸,为维生素 E 类似物,是一种蘑菇酪氨酸酶抑制剂。

Application

当设计基于γ-氨基丁酸(GABA)的抗应激剂时。(R) - (+) - 6-羟基-2,5,7,8-四甲基色满-2-羧酸可用于结合抗氧化性能。


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Inhibitory effects of (S)-and (R)-6-hydroxy-2, 5, 7, 8-tetramethylchroman-2-carboxylic acids on tyrosinase activity.
Yu L.
Journal of Agricultural and Food Chemistry, 51(8), 2344-2347 (2003)
Novel compounds designed as antistress agents.
Tsiakitzis, KC, et al.
Journal of Medicinal Chemistry, 52(22), 7315-7318 (2009)
Aleksandra Slezak et al.
Acta poloniae pharmaceutica, 74(2), 670-678 (2018-04-07)
Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peels (Punica granatunm L.) added at high concentrations (25-100 pg/mL) to V79 (Chinese hamster lung fibroblast) cell cultures, markedly increased intracellular level of ROS (reactive oxygen species). Also



全球贸易项目编号

货号GTIN
391913-1G04061831981254
391913-5G04061831981278