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Merck
CN

438227

羟胺 溶液

50 wt. % in H2O

别名:

HDA

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关于此项目

线性分子式:
NH2OH
化学文摘社编号:
分子量:
33.03
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
232-259-2
MDL number:
Form:
liquid
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vapor pressure

9 mmHg ( 40 °C)

Quality Level

form

liquid

concentration

50 wt. % in H2O

bp

>100 °C

mp

8 °C (46 °F)

solubility

water: soluble

density

1.078 g/mL at 25 °C

storage temp.

room temp

SMILES string

NO

InChI

1S/H3NO/c1-2/h2H,1H2

InChI key

AVXURJPOCDRRFD-UHFFFAOYSA-N

General description

羟胺是一种弱碱,主要用作有机反应中的还原剂。

Application

作为制备下列化合物的反应物:
  • 心血管药物 Nω-羟基-L-精氨酸(NOHA,一氧化氮前体)的前药
  • 羟基氨基胍,作为抗癌药
  • 非甾体2,3-二氢喹啉糖皮质激素受体激动剂,具有降低的磷酸烯醇丙酮酸羧基激酶(PEPCK)转录激活活性
  • 氧氟沙星的羧酰胺衍生物,具有改善的抗菌特性
  • 基于香豆素类似物的TNF-α转化酶(TACE)抑制剂
  • HIV整合酶抑制剂


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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

target_organs

Blood, Respiratory system

存储类别

3 - Flammable liquids

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
438227-1L04065265906920
438227-250ML04061832133102
438227-50ML04061832133157