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Merck
CN

925659

Poly(ethylene glycol)-block-poly(lactide-alt-glycolide)

PEG average Mn 5,000, PLGA Mn 15,000

别名:

PEG-PLGA

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关于此项目

线性分子式:
CH3O(C2H4O)n(C5H6O4)mH
NACRES:
NA.23
UNSPSC Code:
12352112
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form

powder, chunks or granules

Quality Level

mol wt

PEG average Mn 5,000, PLGA Mn 15,000

storage temp.

2-8°C

Application

PEG-PLGA, is a biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(lactide-alternative-glycolide) (PLGA) block. These materials have been used in control release and nanoparticle formulation for drug encapsulation and delivery applications.

Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.

Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Lin Yu et al.
Biomacromolecules, 12(4), 1290-1297 (2011-03-03)
This paper reports the influence of sequence structures of block copolymers composed of poly(lactic acid-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) on their thermogelling aqueous behaviors. A series of thermogelling PLGA-PEG-PLGA triblock copolymers with similar chemical compositions and block lengths



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货号GTIN
925659-1G04065267690087