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A7205

3-乙酰胺基苯酚

Name: 3-乙酰胺基苯酚
Brand: ALDRICH

97%

别名:

3′-羟基乙酰苯胺

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关于此项目

线性分子式:

CH₃CONHC₆H₄OH

化学文摘社编号:

621-42-1

分子量:

151.16

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24891188

EC Number:

210-687-0

Beilstein/REAXYS Number:

907998

MDL number:

MFCD00002263

Assay:

97%

Form:

crystals

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属性

Quality Level

200

assay

97%

form

crystals

mp

145-148 °C (lit.)

SMILES string

CC(=O)Nc1cccc(O)c1

InChI

1S/C8H9NO2/c1-6(10)9-7-3-2-4-8(11)5-7/h2-5,11H,1H3,(H,9,10)

InChI key

QLNWXBAGRTUKKI-UHFFFAOYSA-N

说明

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319

pcodes

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Acetaminophen induces apoptosis of C6 glioma cells by activating the c-Jun NH(2)-terminal protein kinase-related cell death pathway.

M A Bae et al.

Molecular pharmacology, 60(4), 847-856 (2001-09-20)

Acetaminophen (AAP), a widely used analgesic drug, can damage various organs when taken in large doses. In this study, we investigate whether AAP causes cell damage by altering the early signaling pathways associated with cell death and survival. AAP caused

Identification of hepatic protein targets of the reactive metabolites of the non-hepatotoxic regioisomer of acetaminophen, 3'-hydroxyacetanilide, in the mouse in vivo using two-dimensional gel electrophoresis and mass spectrometry.

Y Qiu et al.

Advances in experimental medicine and biology, 500, 663-673 (2002-01-05)

Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3'-hydroxyacetanilide, in mouse liver.

M A Tirmenstein et al.

The Journal of biological chemistry, 264(17), 9814-9819 (1989-06-15)

Acetaminophen (250 mg/kg) administered intraperitoneally to fasted, phenobarbital-induced mice produced hepatotoxicity. No hepatotoxicity was observed after the administration of the regioisomer 3'-hydroxyacetanilide (600 mg/kg). Similar levels of covalent binding to liver homogenates occurred in mice receiving either acetaminophen or 3'-hydroxyacetanilide

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全球贸易项目编号

货号	GTIN
A7205-100G	04061833383797
A7205-25G	04061832281452