B3253
碘化丁酰硫代胆碱
≥98%
别名:
(2-巯乙基)三甲基碘化铵丁酸酯
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关于此项目
线性分子式:
(CH3)3N(I)CH2CH2SCOCH2CH2CH3
化学文摘社编号:
分子量:
317.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
217-475-7
Beilstein/REAXYS Number:
3729509
MDL number:
Assay:
≥98%
Form:
powder
Quality Level
assay
≥98%
form
powder
mp
171-174 °C (lit.)
storage temp.
−20°C
SMILES string
[I-].CCCC(=O)SCC[N+](C)(C)C
InChI
1S/C9H20NOS.HI/c1-5-6-9(11)12-8-7-10(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChI key
WEQAAFZDJROSBF-UHFFFAOYSA-M
General description
碘化丁酰硫胆碱是丁酰胆碱的一种含硫类似物，用作丁酰胆碱酯酶活性测定试剂。
Application
- 丁酰胆碱酯酶的无标记、超灵敏检测：研究采用基于Mn(II)的电子自旋共振波谱法，超灵敏检测丁酰胆碱酯酶。在有机磷农药存在下，以碘化丁酰硫代胆碱为底物测定酶活性。代表生化试验应用。(Tang et al., 2022)。
- 用于生物传感的新型纳米酶：研发开发了一种Co, N共掺的多孔碳基纳米酶，可作为类氧化酶用于丁酰胆碱酯酶的荧光和比色法生物传感检测。其中，碘化丁酰硫代胆碱为关键底物。代表酶动力学分析相关应用(Sun et al., 2022)。
- 抗阿兹海默症′药物筛选的检测系统：研究构建了铜纳米簇和MnO2纳米片荧光检测平台，用于检测丁酰胆碱酯酶活性（利用碘化丁酰硫代胆碱），继而可用于筛选抗阿兹海默病′药物，并检测胆碱能系统相互作用(Chen et al., 2022)。
- 丁酰胆碱酯酶的双通道检测：研究介绍了融合荧光和氧化酶活性的双功能金属有机框架，开发用于双通道检测丁酰胆碱酯酶（使用碘化丁酰硫代胆碱），改进生化试验方法。(Wang et al., 2022)。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Vida Mirzaie et al.
Drug design, development and therapy, 14, 3589-3599 (2020-09-19)
Human butyrylcholinesterase (BChE) serves as a bio scavenger to counteract organophosphate poisoning. It is also a potential drug candidate in several therapeutic fields. Therefore, in the present study, we constructed a new dual-promoter plasmid consisting of Cytomegalovirus (CMV) and human
Gabriela Fernandes et al.
The journal of adhesive dentistry, 22(3), 265-274 (2020-05-22)
To investigate whether dental adhesives modified with polyacrylic acid copper iodide particles could inhibit esterase activity in vitro and the copper release rate from resin matrices, as well as the correlation between the two variables. Different concentrations of copper iodide
Cristobal Narvaez et al.
Chemosphere, 135, 75-82 (2015-04-29)
Inhibition of blood esterase activities by organophosphate (OP) pesticides has been used as a sensitive biomarker in birds. Furthermore, compared to mammalian vertebrates, less is known about the role of these enzyme activities in the digestive tracts of non-mammalian vertebrates
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B3253-25G | 04061833427460 |
| B3253-5G | 04061833427477 |