W224847
4-萜烯醇
≥95%, FCC, FG
别名:
4-松油烯醇
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关于此项目
经验公式（希尔记法）:
C10H18O
化学文摘社编号:
分子量:
154.25
FEMA Number:
2248
Council of Europe no.:
2229
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
2.072
EC Number:
209-235-5
NACRES:
NA.21
MDL number:
Organoleptic:
woody; earthy; pepper
Grade:
FG, Halal
Biological source:
synthetic
Food allergen:
no known allergens
biological source
synthetic
grade
FG, Halal
reg. compliance
EU Regulation 1334/2008 & 872/2012, FCC, FDA 21 CFR 117, FDA 21 CFR 172.515
assay
≥95%
refractive index
n20/D 1.478
bp
88-90 °C
density
0.931 g/mL at 25
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
organoleptic
woody; earthy; pepper
SMILES string
CC(C)C1(O)CCC(C)=CC1
InChI
1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3
InChI key
WRYLYDPHFGVWKC-UHFFFAOYSA-N
General description
自然发生： 茴香，罗勒，黑加仑，可可，香菜，蔓越莓，葡萄柚，柠檬，酸橙，马郁兰，薄荷油，肉豆蔻和留兰香。
Application
- 4-松油醇通过p38MAPK/NF-B信号通路轴（signaling pathway axis）抑制IL-13和粘液产生，从而改善小鼠变应性鼻炎和哮喘综合征。: 展示了4-松油醇在呼吸系统疾病治疗中的抗炎和治疗潜力，突出了其在分子水平上的作用机制（Bezerra Barros et al., 2020）。
Biochem/physiol Actions
味道 30ppm
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 1
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Risa Haigou et al.
Journal of oleo science, 61(1), 35-43 (2011-12-23)
We examined the in vitro metabolism of (+)-terpinen-4-ol by human liver microsomes and recombinant enzymes. The biotransformation of (+)-terpinen-4-ol was investigated by gas chromatography-mass spectrometry (GC-MS). (+)-Terpinen-4-ol was found to be oxidized to (+)-(1R,2S,4S)-1,2-epoxy-p-menthan-4-ol, (+)-(1S,2R,4S)-1,2-epoxy-p-menthan-4-ol, and (4S)-p-menth-1-en-4,8-diol by human liver
Mi-Jin Park et al.
Journal of microbiology (Seoul, Korea), 48(4), 496-501 (2010-08-28)
In this study, the antibacterial activity of essential oil from Chamaecyparis obtusa (Sieb. et Zucc) leaves and twigs was investigated. The test strains were Klebsiella pneumoniae, Listeria monocytogenes, Salmonella typhimurium, Staphylococcus aureus, Escherichia coli, Legionella pneumophila, and Methicilline-resistant Staphylococcus aureus.
Antonella Casiraghi et al.
Pharmaceutical development and technology, 15(5), 545-552 (2009-10-22)
This work aimed to evaluate the effect induced by excipients conventionally used for topical dosage forms, namely isopropyl myristate (IPM) or oleic acid (OA) or polyethylene glycol 400 (PEG400) or Transcutol (TR), on the human skin permeability of terpinen-4-ol (T4OL)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| W224847-1KG | 04061838248930 |
| W224847-250G | 04061837509063 |
| W224847-SAMPLE | 04061838191243 |