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关于此项目
经验公式（希尔记法）:
C27H39D7O
化学文摘社编号:
分子量:
393.70
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141804
Assay:
>99% (TLC)
Form:
powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700056P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
烯胆甾烷醇是存在于人母乳中的胆固醇代谢物。烯胆甾烷醇由烯胆甾烷醇5-去饱和酶分解为7-脱氢胆固醇，这是胆固醇的前体。烯胆甾烷醇-d7是烯胆甾烷醇的氘代衍生物。
Application
烯胆甾烷醇-d7已被用作用于母乳甾醇定量的气相色谱-质谱（GC-MS）的内标物，和液相色谱-高分辨率质谱（LC-HRMS）分析的内标物。
Biochem/physiol Actions
烯胆甾烷醇水平是胆固醇水平的直接指标，有助于解码代谢缺陷。烯胆甾烷醇水平升高与脑腱黄瘤病（CTX）和烯胆甾烷醇病有关。烯胆甾烷醇5-去饱和酶（SC5D）失活导致烯胆甾烷醇在烯胆甾烷醇病病理学中积累。
Packaging
5 mL琥珀色玻璃螺旋盖样品瓶(700056P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
Patrycja A Krakowiak et al.
Human molecular genetics, 12(13), 1631-1641 (2003-06-19)
Lathosterol 5-desaturase catalyzes the conversion of lathosterol to 7-dehydrocholesterol in the next to last step of cholesterol synthesis. Inborn errors of cholesterol synthesis underlie a group of human malformation syndromes including Smith-Lemli-Opitz syndrome, desmosterolosis, CHILD syndrome, CDPX2 and lathosterolosis. We
Alan H B Wu et al.
Clinica chimica acta; international journal of clinical chemistry, 430, 43-47 (2014-01-08)
The analysis of blood for β-sitosterol and campesterol is the measures of cholesterol absorption while lathosterol is a measure of cholesterol synthesis. The biological variability of β-sitosterol, campesterol, and lathosterol was measured using liquid-chromatography tandem mass spectrometry from a cohort
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 700056P-1MG | 04061835189182 |