产品名称
14：0 Lyso PA, 1-myristoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder
assay
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
form
powder
packaging
pkg of 1 × 25 mg (857120P-25mg), pkg of 1 × 500 mg (857120P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 857120P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCC)=O.[Na+]
InChI
1S/C17H35O7P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(19)23-14-16(18)15-24-25(20,21)22;/h16,18H,2-15H2,1H3,(H2,20,21,22);/q;+1/p-1/t16-;/m1./s1
InChI key
HGENTPHNTSLRPB-PKLMIRHRSA-M
General description
溶血磷脂酸（LPA）属于磷脂类，其甘油主链由磷酸基、脂肪链和羟基连接而成。它的磷酸基连接到sn-3位，脂肪链连接到sn-1或sn-2位，羟基连接到其余sn-1或sn-2位。
Application
14:0 Lyso PA适合用作内标物以加标血清样品以提取血清脂质。它也适用于在多反应监测（MRM）分析中用作脂质提取和质量控制的标准脂质。
Biochem/physiol Actions
溶血磷脂酸（LPA）参与多种生物学功能。它是检测卵巢癌的潜在生物标志物。LPA可刺激血小板聚集、平滑肌收缩、趋化、细胞骨架重排、Ca2+动员、神经递质释放和细胞增殖。
Packaging
20 mL透明玻璃螺旋盖小瓶（857120P-500mg）
5 mL棕色玻璃螺旋盖小瓶（857120P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Determination of lysophosphatidic acids by capillary electrophoresis with indirect ultraviolet detection
Chen YL and Xu Y
Journal of Chromatography. B, Biomedical Sciences and Applications, 753(2), 355-363 (2001)
Ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry for accurate analysis of glycerophospholipids and sphingolipids in drug resistance tumor cells
Li L, et al.
Journal of Chromatography A, 1381(2), 140-148 (2015)
Olaposi I Omotuyi et al.
Scientific reports, 5, 13343-13343 (2015-08-14)
Lysophosphatidic acid (LPA) receptor 1 (LPA1) is a member of the G protein-coupled receptors mediating the biological response to LPA species. Lack of detailed mechanism underlying LPA/LPA1 interaction has hampered the development of specific antagonists. Here, novel N-terminal Lys39 has
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 857120P-25MG | 04061835231898 |
| 857120P-500MG | 04061835231904 |