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Merck
CN

A-096

醛固酮标准液 溶液

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

别名:

醛固酮, 11β,21-二羟基-3,20-二氧代-4-孕-18-烯醛, 11β,21-二羟孕-4-烯-3,18,20-三酮, 18-醛固酮, Reichstein X

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关于此项目

经验公式(希尔记法):
C21H28O5
化学文摘社编号:
分子量:
360.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-835-2
Beilstein/REAXYS Number:
3224996
MDL number:
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grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@]4(C[C@H](O)[C@H]23)C=O

InChI

1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1

InChI key

PQSUYGKTWSAVDQ-ZVIOFETBSA-N

General description

醛固酮是盐皮质激素家族中的一种激素,可刺激钠跨细胞膜转运,并有助于维持血压和血容量。通过LC-MS/MS测量血清/血浆和尿液中的醛固酮水平,以检测从肾上腺皮质继发性醛固酮增多症到肾血管疾病和Bartter综合征的原发性或增生的检查。

Application

醛固酮的D-异构体被认为是具有生物活性的异构体。

Other Notes

以醛和半缩醛的平衡混合物形式存在。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany


pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

法规信息

危险化学品

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实验方案

The conversion of clinical methods to LC/MS/MS offers advantages; however, is accompanied by a few limitations, notably interference effects from the endogenous sample matrix.