05-1938
Anti-G3BP1 Antibody, clone 14E5-G9
clone 14E5-G9, from mouse
别名:
ATP-dependent DNA helicase VIII, GAP SH3 domain-binding protein 1, GAP binding protein, GTPase activating protein (SH3 domain) binding protein 1, Ras-GTPase-activating protein SH3-domain-binding protein, RasGAP-associated endoribonuclease G3BP
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关于此项目
eCl@ss:
32160702
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
14E5-G9, monoclonal
Application:
ICC, WB
Citations:
-
biological source
mouse
Quality Level
conjugate
unconjugated
antibody product type
primary antibodies
clone
14E5-G9, monoclonal
species reactivity
human
technique(s)
immunocytochemistry: suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... G3BP1(10146)
General description
G3BP1 (Ras-GTPase activating protein SH3-domain binding protein 1) directly associates with SH3 domains of GTPase activating proteins (GAPs). It was first discovered by its binding to RasGAP. G3BPs have been shown to be involved in a number of mitogenic signaling pathways. G3BP1 is also known to be over expressed in many human cancers (Kim, 2007) and its expression appears to be inversely correlated with PTEN expression (Kim, 2007). Interestingly, G3BP1, along with G3BP2, has been shown to bind to the C-terminus of p53, playing a crucial role in its activity (Kim, 2007). Furthermore, the G3BPs have two traditional RNA binding motifs.
52 kDa
Immunogen
GST-tagged recombinant protein corresponding to human G3BP1.
Application
Anti-G3BP1 Antibody, clone 14E5-G9 is an antibody against G3BP1 for use in WB & IC.
Research Sub Category
RNA Metabolism & Binding Proteins
G-proteins
RNA Metabolism & Binding Proteins
G-proteins
Biochem/physiol Actions
This antibody recognizes G3BP1.
Physical form
Format: Purified
Analysis Note
Evaluated by Western Blot in K562 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected G3BP1 on K562 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected G3BP1 on K562 cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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