biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
6F-H2, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... WT1(7490)
General description
55-60kDa
Immunogen
6His标记融合蛋白,对应人WT1(维尔姆斯瘤)的1-181位残基。
Application
抗-WT1抗体(克隆6F-H2)是一种用于检测WT1(又称维尔姆斯瘤)的小鼠单克隆抗体,目前已通过WB、ICC & IHC应用验证。
Biochem/physiol Actions
WT1
Physical form
形式:纯化
Analysis Note
已通过免疫印迹对Jurkat和Raji细胞的RIPA裂解液进行常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Toru Sakairi et al.
American journal of physiology. Renal physiology, 298(3), F557-F567 (2009-12-04)
Evidence suggests that loss of podocytes into urine contributes to development of glomerular diseases; shed podocytes are frequently viable and proliferate in culture conditions. To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term
Rosalba Parenti et al.
PloS one, 9(12), e114333-e114333 (2014-12-05)
Wilms' tumor gene 1 (WT1) plays complex roles in tumorigenesis, acting as tumor suppressor gene or an oncogene depending on the cellular context. WT1 expression has been variably reported in both benign and malignant peripheral nerve sheath tumors (MPNSTs) by
Aleksandra Rak-Raszewska et al.
Organogenesis, 8(4), 125-136 (2012-10-23)
Embryonic stem cells (ESC) are self-renewing and can generate all cell types during normal development. Previous studies have begun to explore fates of ESCs and their mesodermal derivatives after injection into explanted intact metanephric kidneys and neonatal kidneys maturing in