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Merck
CN

07-324

抗-PP2A抗体(C亚基 )

Upstate®, from rabbit

别名:

Anti-NEDLBA, Anti-PP2Ac, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
9
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

bovine, rat, human, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PPP2CA(5515)

General description

36kDa

Immunogen

对应于人PP2A氨基酸290-304(DPAPRRGEPHVTRRT)的肽

Application

研究子类别
氧化应激

神经退行性疾病
研究类别
信号传导

神经科学
该抗-PP2A抗体(C亚基)经过验证可用于WB检测PP2A。

Biochem/physiol Actions

PP2A催化亚基

Physical form

0.2M Tris-甘氨酸(pH 7.4)、0.15M NaCl、0.05%叠氮化钠、5mg/ml BSA,然后添加甘油至30%
免疫亲和层析

Preparation Note

在-20°C下可保存2年

Analysis Note

已通过免疫印迹对小鼠脑、心脏、睾丸和肾脏匀浆液的RIPA裂解液进行常规评估

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

10 - Combustible liquids

wgk

WGK 2



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Characterization of SET/I2PP2A isoforms in dogs.
Yabe, R; Fujiwara, N; Mizuno, T; Usui, T; Ohama, T; Sato, K
The Journal of Veterinary Medical Science null
Satoru Kake et al.
Scientific reports, 7(1), 4279-4279 (2017-06-29)
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer. Ser/Thr protein phosphatase 2A (PP2A) plays a critical role as a tumor suppressor, and SET/I2PP2A
Ha Yin Lee et al.
Science signaling, 11(512) (2018-01-11)
Cancer cells increase glucose metabolism to support aerobic glycolysis. However, only some cancer cells are acutely sensitive to glucose withdrawal, and the underlying mechanism of this selective sensitivity is unclear. We showed that glucose deprivation initiates a cell death pathway



全球贸易项目编号

货号GTIN
07-32404053252581946