biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
shipped in
dry ice
target post-translational modification
dimethylation (Arg)
General description
不能识别非甲基化肽、含有不对称二甲基精氨酸的肽或含有单一对称二甲基精氨酸的肽。
变化
精氨酸甲基化是翻译后修饰,导致形成不对称和对称的二甲基化精氨酸(a-和sDMA)。
Immunogen
一种含有四个对称二甲基-精氨酸-甘氨酸重复序列的肽
Application
抗二甲基-精氨酸抗体,对称性(SYM10)是一种高质量的兔多克隆抗体,用于检测二甲基-精氨酸,&已在ICC、IP & WB中得到验证。
研究子类别
染色质生物学
染色质生物学
研究类别
信号传导
信号传导
Biochem/physiol Actions
识别含有多个对称二甲基化精氨酸的蛋白,包括p80-Coilin和Sm蛋白B、B′和D。
Physical form
含0.05%叠氮化钠和30%甘油的全兔抗血清。 在-20°C为液体形式。
Preparation Note
自收到之日起在-20°C可稳定保存1年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。
Analysis Note
对照
阳性抗原对照:目录# 12-303,Jurkat细胞裂解液。
阳性抗原对照:目录# 12-303,Jurkat细胞裂解液。
通过免疫印迹对Jurkat细胞的RIPA裂解液进行了常规评估
Other Notes
浓度:请参考批次特异性浓缩物的分析证书。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Xiaodi Xu et al.
Journal of fungi (Basel, Switzerland), 7(10) (2021-10-24)
Penicillium expansum is one of the most common and destructive post-harvest fungal pathogens that can cause blue mold rot and produce mycotoxins in fruit, leading to significant post-harvest loss and food safety concerns. Arginine methylation by protein arginine methyltransferases (PRMTs)
Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing.
Deng, X; Gu, L; Liu, C; Lu, T; Lu, F; Lu, Z; Cui, P; Pei, Y; Wang, B; Hu, S; Cao, X
Proceedings of the National Academy of Sciences of the USA null
Lindsay M Webb et al.
Frontiers in immunology, 10, 524-524 (2019-04-04)
Multiple sclerosis is an autoimmune disease of the central nervous system (CNS) mediated by CD4+ T cells and modeled via experimental autoimmune encephalomyelitis (EAE). Inhibition of PRMT5, the major Type II arginine methyltransferase, suppresses pathogenic T cell responses and EAE.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 07-412 | 04053252369377 |