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Merck
CN

1.07427

对羟基苯甲酸丙酯

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, NF

别名:

Propyl 4-hydroxybenzoate, Propylparaben

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关于此项目

经验公式(希尔记法):
C10H12O3
化学文摘社编号:
分子量:
180.20
UNSPSC Code:
12352108
EC Index Number:
202-307-7
MDL number:
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Quality Level

agency

BP, ChP, JP, NF, Ph. Eur.

vapor pressure

0.67 hPa ( 122 °C)

product line

EMPROVE® EXPERT

form

solid

autoignition temp.

>600 °C

potency

>5000 mg/kg LD50, oral (Rat)

technique(s)

API processing | cocrystal formation: suitable

pH

6-7 (20 °C in H2O, saturated solution)

mp

96-98 °C

transition temp

flash point 180 °C

solubility

0.4 g/L

density

1.063 g/cm3 at 102 °C

application(s)

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

O(CCC)C(=O)c1ccc(cc1)O

InChI

1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3

InChI key

QELSKZZBTMNZEB-UHFFFAOYSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.


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hcodes

Hazard Classifications

Aquatic Chronic 3

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

356.0 °F

flash_point_c

180 °C



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全球贸易项目编号

货号GTIN
107427002504022536090641
107427500004022536090658
107427902904022536938714