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14-304

MKK6/SKK3 Protein, inactive, 50 g

Name: MKK6/SKK3 Protein, inactive, 50 g
Brand: MM

Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.

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关于此项目

UNSPSC Code:

12352202

NACRES:

NA.32

eCl@ss:

32160405

Biological source:

human

Recombinant:

expressed in E. coli

Mol wt:

M_w 80.6 kDa

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属性

biological source

human

Quality Level

100

recombinant

expressed in E. coli

mol wt

M_w 80.6 kDa

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_002758.3

UniProt accession no.

P52564

shipped in

dry ice

Gene Information

human ... MAP2K6(5608)

说明

General description

Product Source: expressed in E. coli

Recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag

Biochem/physiol Actions

Protein Target: MKK6

Target Sub-Family: STE

Physical form

affinity chromatography on amylose resin beads

Preparation Note

6 months at -70C

Analysis Note

routinely evaluated by phosphorylation of MBP

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

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Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells.

R Meier et al.

European journal of biochemistry, 236(3), 796-805 (1996-03-15)

The identities of the upstream activators of the mitogen-activated protein (MAP) kinase homologues termed stress-activated-protein (SAP) kinase-1 (also known as JNK or SAPK) and SAP kinase-2 (also known as p38, RK and CSBP) were investigated in rat PC12 cells and

MRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrest.

Eleanore A Gross et al.

The Journal of biological chemistry, 277(16), 13873-13882 (2002-02-12)

Mitogen-activated protein (MAP) kinase pathways are three-kinase modules that mediate diverse cellular processes and have been highly conserved among eukaryotes. By using a functional complementation screen in yeast, we have identified a human MAP kinase kinase kinase (MAPKKK) that shares

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.

M Goedert et al.

The EMBO journal, 16(12), 3563-3571 (1997-06-01)

A cDNA was cloned that encodes human stress-activated protein kinase-4 (SAPK4), a novel MAP kinase family member whose amino acid sequence is approximately 60% identical to that of the other three SAP kinases which contain a TGY motif in their

全球贸易项目编号

货号	GTIN
14-304	04053252742385
CAD7956-12EA	04061832518411