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Merck
CN

AB15794

抗-Dexras1抗体

Chemicon®, from rabbit

别名:

Activator of G-Protein Signaling 1, AGS1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
15
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

rat (100% immunogen homology), human (100% immunogen homology)

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... RASD1(51655)

General description

Dexras1是Ras-G-蛋白超家族的成员,直接与Gialpha异源三聚体G蛋白结合,它似乎促进Gialpha上的鸟嘌呤核苷酸交换。Dexras1通过一氧化氮合酶参与NMDA受体信号传导。

Immunogen

合成肽。

Application

研究子类别
信号神经科学
研究类别
神经科学
蛋白质印迹:1:1,000,小鼠脑提取物中。
最佳工作稀释度必须由最终用户进行确定。
该抗Dexras1抗体经过验证可用于WB中,以用于检测Dexras1。

Biochem/physiol Actions

Dexras1(G蛋白信号传导激活剂1,AGS1)。抗体通过蛋白质印迹识别小鼠脑提取物的~33 kDa的条带。该抗体还被用于检测棕色脂肪细胞裂解液中的Dexras1。
其他物种尚未经过测试

Physical form

免疫亲和纯化
溶于PBS中的液体。不含防腐剂

Preparation Note

自发货之日起可在-70°C保存6个月

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

存储类别

12 - Non Combustible Liquids



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M J Cismowski et al.
The Journal of biological chemistry, 275(31), 23421-23424 (2000-06-07)
Utilizing a functional screen in the yeast Saccharomyces cerevisiae we identified mammalian proteins that activate heterotrimeric G-protein signaling pathways in a receptor-independent fashion. One of the identified activators, termed AGS1 (for activator of G-protein signaling), is a human Ras-related G-protein
M J Cismowski et al.
Nature biotechnology, 17(9), 878-883 (1999-09-03)
We describe genetic screens in Saccharomyces cerevisiae designed to identify mammalian nonreceptor modulators of G-protein signaling pathways. Strains lacking a pheromone-responsive G-protein coupled receptor and expressing a mammalian-yeast Galpha hybrid protein were made conditional for growth upon either pheromone pathway
Ras dexamethasone-induced protein 1 is a modulator of hormone secretion in the volume overloaded heart.
McGrath, MF; Ogawa, T; de Bold, AJ
American Journal of Physiology. Heart and Circulatory Physiology null



全球贸易项目编号

货号GTIN
AB1579404053252677618