biological source
mouse
Quality Level
conjugate
ALEXA FLUOR™ 488
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
113-1, monoclonal
species reactivity
human (mitochondria protein)
should not react with
mouse (mitochondria protein), rat (mitochondria protein)
technique(s)
immunocytochemistry: suitable
isotype
IgG1
shipped in
wet ice
target post-translational modification
unmodified
General description
计算值为60 kDa
该抗体可识别人细胞中线粒体的60 kDa非糖基化蛋白组分。它可用于染色细胞、组织或生化制剂中的线粒体,并可用作亚细胞组分中线粒体的标志物。MAB1273A4通过免疫沉淀识别65 kD的蛋白,并在人细胞的细胞质中产生条状的“意大利面条状”染色模式。
Application
使用经验证可用于ICC的小鼠单克隆抗体(抗线粒体抗体,克隆113-1 &Alexa Fluor™488偶联物)检测线粒体标记物。
通过免疫细胞化学在原代小鼠胚胎成纤维细胞(PMEF)中进行评估。
免疫细胞化学分析:该抗体的1:50稀释液未在原代小鼠胚胎成纤维细胞(PMEF)中检测到线粒体。
免疫细胞化学分析:该抗体的1:50稀释液未在原代小鼠胚胎成纤维细胞(PMEF)中检测到线粒体。
Analysis Note
通过免疫细胞化学在人脂肪间充质干细胞(SCC038)中进行评估。
免疫细胞化学分析:该抗体的1:50稀释液在人脂肪间充质干细胞(SCC038)中检测到线粒体。
免疫细胞化学分析:该抗体的1:50稀释液在人脂肪间充质干细胞(SCC038)中检测到线粒体。
Other Notes
浓度:请参考批次特异性浓缩物的分析证书。
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Anna C Krieger et al.
Cancers, 15(10) (2023-06-22)
Cardiolipin (CL) is a mitochondrial lipid with diverse roles in cellular respiration, signaling, and organelle membrane structure. CL content and composition are essential for proper mitochondrial function. Deranged mitochondrial energy production and signaling are key components of glial cell cancers
Markus Pasztorek et al.
Frontiers in bioengineering and biotechnology, 7, 338-338 (2019-12-06)
The mechanobiological behavior of mesenchymal stem cells (MSCs) in two- (2D) or three-dimensional (3D) cultures relies on the formation of actin filaments which occur as stress fibers and depends on mitochondrial dynamics involving vimentin intermediate filaments. Here we investigate whether
Wen Yang et al.
Cell, 167(4), 985-1000 (2016-11-25)
Mitochondrial sirtuins, SIRT3-5, are NAD+-dependent deacylases and ADP-ribosyltransferases that are critical for stress responses. However, a comprehensive understanding of sirtuin targets, regulation of sirtuin activity, and the relationships between sirtuins remains a key challenge in mitochondrial physiology. Here, we employ
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB1273A4 | 04053252918315 |