产品名称
Anti-Integrin β1 Antibody, active β1 integrins, clone TASC/9D11, clone TASC/9D11, Chemicon®, from mouse
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
TASC/9D11, monoclonal
species reactivity
chicken
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGB1(3688)
Immunogen
E10 chick brain glial cells
Epitope: active beta1 integrins
Application
Detect the Integrin β1 protein using this Anti-Integrin β1, active β1 integrins, clone TASC/9D11 validated for use in IP & ICC.
Western blot: Not effective
Immunocytochemistry
Immunoprecipitation
Biological activity: Functionally inhibits attachment to vitronectin. Activates attachment to other substrates.
Optimal working dilutions must be determined by end user.
Immunocytochemistry
Immunoprecipitation
Biological activity: Functionally inhibits attachment to vitronectin. Activates attachment to other substrates.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Reactive with the extracellular domain of chicken integrin beta 1
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB +0.25 M NaCl, pH=7.6 with 0.1% Sodium Azide.
Preparation Note
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Vitronectin and thrombospondin promote retinal neurite outgrowth: developmental regulation and role of integrins.
Neugebauer, K M, et al.
Neuron, 6, 345-358 (1991)
L R Strachan et al.
Experimental cell research, 314(3), 441-452 (2007-11-27)
Cell migration is essential for proper development of numerous structures derived from embryonic neural crest cells (NCCs). Although recent work has shown that receptor recycling plays an important role in NCC motility on laminin, the molecular mechanisms regulating NCC motility
Cell-surface regulation of beta 1-integrin activity on developing retinal neurons.
Neugebauer, K M and Reichardt, L F
Nature, 350, 68-71 (1991)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB19294 | 04053252319006 |