description
C3H4O6PK (Formula), PEP, monopotassium salt
assay
97% (PEP-K)
form
solid
mol wt
Mr 168.0 (PEP), Mr 206.1 (PEP-K)
packaging
pkg of 1 g
manufacturer/tradename
Roche
storage temp.
2-8°C
SMILES string
[K+].OC(=O)C(=C)OP(O)([O-])=O
InChI
1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1
InChI key
SOSDSEAIODNVPX-UHFFFAOYSA-M
General description
内容物： 80%PEP（酶法）
Application
磷酸烯醇式丙酮酸 (PEP) 已用于：
- 谷氨酸-半胱氨酸连接酶活性
- v-ATPase 酶活性测定
- meso 激酶测定
丙酮酸激酶的底物。
Biochem/physiol Actions
磷酸烯醇丙酮酸 (PEP) 在代谢中起重要作用。它具有较高的磷酸基团转移潜能，在C-C，C-P 和 C-O 键形成反应中起着通用的 C3-合成子的作用。PEP 在糖酵解的最后一步充当丙酮酸激酶 (PK) 的底物。
Other Notes
仅用于生命科学研究。不可用于诊断。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes.
Garcia A, et al.
FEBS Journal, 269(13), 3226-3236 (2002)
Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells.
Desideri E
Autophagy, 8(12), 1769-1781 (2012)
Maria B Bagh et al.
Nature communications, 8, 14612-14612 (2017-03-08)
Defective lysosomal acidification contributes to virtually all lysosomal storage disorders (LSDs) and to common neurodegenerative diseases like Alzheimer's and Parkinson's. Despite its fundamental importance, the mechanism(s) underlying this defect remains unclear. The v-ATPase, a multisubunit protein complex composed of cytosolic
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 10108294001 | 04061838666932 |