07964
甲氧基聚乙二醇胺
750 MW
别名:
mPEG-NH2, O-(2-氨基乙基)-O′-甲基聚乙二醇, 氨基聚乙二醇单甲醚, 甲氧基聚氧乙烯胺
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关于此项目
线性分子式:
H2NCH2CH2(OCH2CH2)nOCH3
化学文摘社编号:
NACRES:
NA.22
UNSPSC Code:
12162002
MDL number:
Form:
solid
Quality Level
form
solid
color
white to yellow
InChI
1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3
InChI key
ASUDFOJKTJLAIK-UHFFFAOYSA-N
Application
甲氧基聚乙二醇胺可以：
- 形成树枝状胶束，增强疏水性化合物的溶解性。
- 与抗癌药物甲氨蝶呤（MTX）共轭形成 MTX-PEG，一种潜在的药物载体。
- 与聚乙烯亚胺（PEI）形成接枝共聚物，一种潜在的非病毒基因载体。
Other Notes
用于制备聚乙二醇化共轭物的低聚物，该共轭物具有降低免疫原性和延长血清半衰期的优势
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.
Effect of polyethylene glycol on gene delivery of polyethylenimine.
Sung SJ, et al.
Biological & Pharmaceutical Bulletin, 26(4), 492-500 (2003)
M Yokoyama et al.
Bioconjugate chemistry, 3(4), 295-301 (1992-07-01)
Adriamycin, a hydrophobic anticancer drug, was conjugated with poly(ethylene oxide)-poly(aspartic acid) block copolymers composed of various lengths of each block copolymer segment ranging from 1000 to 12,000 in molecular weight and from 10 to 80 units, respectively. Conjugation was achieved
Polyethylene Glycol Conjugates of Methotrexate Varying in Their Molecular Weight from MW 750 to MW 40000: Synthesis, Characterization, and Structure- Activity Relationships in Vitro and in Vivo.
Riebeseel K, et al.
Bioconjugate Chemistry, 13(4), 773-785 (2002)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| V900708-500G | 04061832114002 |
| 246352-100G | 04061825858845 |
| 246352-500G | 04061838347923 |
| V900708-100G | 04061832113999 |
| 07964-1G | 04061826661352 |
| 07964-250MG | 04061833489727 |