63177
6-(马来酰亚胺基)己酸琥珀酰亚胺酯
≥98.0% (HPLC)
别名:
6-马来酰亚氨基己酸 N-琥珀酰亚胺酯, N-(ε-马来酰亚胺己酰氧)琥珀酰亚胺, N-琥珀酰亚胺 6-马来酰亚胺己酸酯, EMCS
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关于此项目
经验公式（希尔记法）:
C14H16N2O6
化学文摘社编号:
分子量:
308.29
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1499815
Assay:
≥98.0% (HPLC)
Form:
solid
Quality Level
assay
≥98.0% (HPLC)
form
solid
reaction suitability
reagent type: linker
mp
70-73 °C (lit.)
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
InChI
1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI key
VLARLSIGSPVYHX-UHFFFAOYSA-N
Application
6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Reagent for cross-linking and immobilisation of proteins
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
T. Kitagawa
Enzyme Immunoassay, 81-81 (1981)
Preparation and characterization of hetero-bifunctional cross-linking reagents for protein modifications.
Kitagawa, T., et al.
Chemical & Pharmaceutical Bulletin, 29, 1130-1130 (1981)
Mitsuko Maeda et al.
Bioorganic & medicinal chemistry letters, 15(3), 621-624 (2005-01-25)
The adenovirus vector is a promising carrier for the efficient transfer of genes into cells via the coxackie-adenovirus receptor (CAR) and integrins (alphavbeta3 and alphavbeta5). The clinical use of the adenovirus vector remains problematic however. Successful administration of this vector
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