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关于此项目
经验公式(希尔记法):
C21H41NO4
化学文摘社编号:
分子量:
371.55
NACRES:
NB.21
UNSPSC Code:
41116107
MDL number:
Beilstein/REAXYS Number:
4149853
grade
analytical standard
Quality Level
assay
≥97.0% (HPLC)
optical activity
[α]/D -18.0±2.0°, c = 1 in methanol
shelf life
limited shelf life, expiry date on the label
impurities
≤10.0% water
application(s)
clinical testing
format
neat
storage temp.
2-8°C
SMILES string
C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCC)=O)CC([O-])=O
InChI
1S/C21H41NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-21(25)26-19(17-20(23)24)18-22(2,3)4/h19H,5-18H2,1-4H3/t19-/m1/s1
InChI key
PSHXNVGSVNEJBD-LJQANCHMSA-N
General description
肉豆蔻酰基-L-肉碱属于酰基-L-肉碱类化合物,其是源自氨基酸和脂肪酸分解的L-肉碱的乙酰化形式。据报道,这些化合物可用作肉毒碱缺乏诊断中的生物标志物。
Application
肉豆蔻酰基-L-肉碱可用作分析标准品,通过使用与三重四极杆-LC MS/MS偶联的高效液相色谱法测定玉米植物中分析物的含量。肉碱的外源应用刺激了脂肪酸向线粒体的运输,并研究了在正常和冷冻条件下生长的玉米叶片中肉碱对细胞质、线粒体基质和线粒体呼吸之间脂质运输的可能效应作用。
可以用作以下过程中的分析标准品:
可以用作以下过程中的分析标准品:
- 使用高效液相色谱串联质谱法(HPLC-MS/MS)分离和鉴别人血浆样品中未衍生化的肉豆蔻酰基-L-肉碱。
- 使用高效液相色谱(HPLC)结合电喷雾电离-串联质谱法(ESI-MS/MS)测定干血样中的分析物。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Matrix effect?corrected liquid chromatography/tandem mass-spectrometric method for determining acylcarnitines in human urine
Abe K, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 468, 187-194 (2017)
Ralph Fingerhut et al.
Analytical chemistry, 81(9), 3571-3575 (2009-03-28)
Electrospray ionization-tandem mass spectrometry (ESI-MS/MS) is increasingly used in newborn screening programs. Acylcarnitine profiles from dried blood spots (DBS) are used to detect fatty acid oxidation disorders, carnitine cycle disorders, and organic acidurias. Stored dried blood is also a valuable
Minzhi Peng et al.
Journal of chromatography. A, 1319, 97-106 (2013-10-31)
A simple HPLC-MS/MS method has been established to separate and identify underivatized acylcarnitine isomers. Human plasma samples were deproteinized and concentrated. Acylcarnitines were separated on a reverse phase column and detected with triple quadrupole linear ion trap mass spectrometry. Deuterium-labeled
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 91582-10MG | 04061834157199 |
| 91582-50MG | 04061834157205 |