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PHR1630

醋酸泼尼松龙

Name: 醋酸泼尼松龙
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

1,4-孕甾二烯-11β,17α,21-三醇-3,20-二酮 21-醋酸酯, 11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮 21-醋酸酯, 21-乙酰氧基-1,4-孕甾二烯-11β,17α-二醇-3,20-二酮

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关于此项目

经验公式（希尔记法）:

C₂₃H₃₀O₆

化学文摘社编号:

52-21-1

分子量:

402.48

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823520

EC Number:

200-134-1

Beilstein/REAXYS Number:

3111798

MDL number:

MFCD00037710

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属性

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. P2800000, traceable to USP 1556008

API family

prednisolone

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h6,8,10,16-18,20,26,28H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

InChI key

LRJOMUJRLNCICJ-JZYPGELDSA-N

Gene Information

human ... NR3C1(2908)

说明

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Prednisolone Acetate belongs to the group of glucocorticoids, widely used to treat allergic and inflammatory conditions of the eyes.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Prednisolone Acetate may be used as a secondary pharma standard for the determination of the analyte in pharmaceutical formulations using high-performance liquid chromatography technique.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC0028 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

GHS08

signalword

Danger

hcodes

H360FD

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

法规信息

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Simultaneous determination of ofloxacin, tetrahydrozoline hydrochloride, and prednisolone acetate by high-performance liquid chromatography.

Mohammed Shahid Ali et al.

Journal of chromatographic science, 40(8), 429-433 (2002-10-22)

A simple, specific, and precise high-performance liquid chromatographic method has been developed for the simultaneous determination of ofloxacin (OFX), tetrahydrozoline hydrochloride (THC), and prednisolone acetate (PAC) in ophthalmic suspension using propylparaben (POP) as the internal standard. The mobile phase consists

Stability indicating HPLC method for the simultaneous determination of moxifloxacin and prednisolone in pharmaceutical formulations

Razaaq NS, et al.

Chemistry Central Journal, 6(1), 94-94 (2012)

全球贸易项目编号

货号	GTIN
PHR1630-1G	04061835238095