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Merck
CN

B4380

溴乙烷

≥97% purity, powder

别名:

单溴代二苯甲烷

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关于此项目

经验公式(希尔记法):
C10H11BrN2O2
化学文摘社编号:
分子量:
271.11
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
4430959
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产品名称

溴乙烷, ≥97% (HPLC)

Quality Level

assay

≥97% (HPLC)

form

powder

color

yellow

mp

161 °C

solubility

acetonitrile: 20 mg/mL

ε (extinction coefficient)

4.6-5.1 at 396-398 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CC1=C(C)C(=O)N2N1C(CBr)=C(C)C2=O

InChI

1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3

InChI key

AHEWZZJEDQVLOP-UHFFFAOYSA-N

General description

溴代双满又称单溴联苯胺。它还是一种已知的硫醇探针,是一种在光解反应后活化的荧光试剂。

Application

溴代双满用于高效液相色谱法硫醇测定,适于荧光测定2,3-二巯基丙烷-1-磺酸和其他二硫醇。溴代双满已用作研究牛心线粒体寡霉素敏感性 ATP 酶的荧光标记。
此物质可用于体外游离硫化氢的定量测定。它已用于标记含有硫醇基的蛋白质。

Biochem/physiol Actions

溶液形式的溴代双满可与小分子硫醇基(如 GSH)和反应性蛋白硫醇基(如血红蛋白)反应。溴代双满与硫醇的反应为二级pH依赖性反应,且在与硫醇盐反应后,可活化水溶性荧光产物以便检测。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bromobimane probes for thiols.
E M Kosower et al.
Methods in enzymology, 251, 133-148 (1995-01-01)
N S Kosower et al.
Proceedings of the National Academy of Sciences of the United States of America, 76(7), 3382-3386 (1979-07-01)
The bimane fluorescent labels, monobromobimane, dibromobimane, and monobromotrimethylammoniobimane, are derivatives of syn-9,10-dioxabimane:1,5-diazabicyclo[3.3.0]octa-3,6-diene-2,8-dione. They efficiently label hemoglobin (reactive thiol groups), membrane proteins, and glutathione of normal human red cells under physiological conditions. Monobromobimane and dibromobimane are effective on intact cells while
Differing effects of mechanical dough development and sheeting development methods on aggregated glutenin proteins.
Sutton KH, et al.
Cereal Chem., 80.6, 707-711 (2003)



全球贸易项目编号

货号GTIN
B4380-25MG04061833429617
B4380-100MG04061833429594