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Merck
CN

H6878

8-羟基喹啉

别名:

8-羟基喹啉, 8-氢氧化喹啉, 8-羟基氮杂萘, 喔星

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关于此项目

经验公式(希尔记法):
C9H7NO
化学文摘社编号:
分子量:
145.16
UNSPSC Code:
12352005
NACRES:
NA.21
PubChem Substance ID:
EC Number:
205-711-1
Beilstein/REAXYS Number:
114512
MDL number:
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assay

≥98.5%

Quality Level

form

powder (or crystalline powder or flakes)

mp

72.5-74.0 °C

antibiotic activity spectrum

fungi

mode of action

DNA synthesis | interferes, enzyme | inhibits

SMILES string

Oc1cccc2cccnc12

InChI

1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChI key

MCJGNVYPOGVAJF-UHFFFAOYSA-N

General description

化学结构:喹诺酮

Application

用作亲脂性单质双齿螯合剂。


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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María Isabel Fernández-Bachiller et al.
Journal of medicinal chemistry, 53(13), 4927-4937 (2010-06-16)
Tacrine and PBT2 (an 8-hydroxyquinoline derivative) are well-known drugs that inhibit cholinesterases and decrease beta-amyloid (Abeta) levels by complexation of redox-active metals, respectively. In this work, novel tacrine-8-hydroxyquinoline hybrids have been designed, synthesized, and evaluated as potential multifunctional drugs for
Bhimashankar Mitkari et al.
Experimental neurology, 239, 158-162 (2012-10-13)
Cell therapies from various sources have been under intense research in stroke. Efficient homing of the cells to the injured brain without complications is necessary to realize the therapeutic potential of cell therapy. Intra-arterial (IA) infusion of cells bypasses the
Mahmud Tareq Hassan Khan et al.
Journal of medicinal chemistry, 52(1), 48-61 (2008-12-17)
In the present work, 22 compounds of the U.S. NCI compound library (size 273K) were identified as putative thermolysin binders by structure based virtual screening with the ICM software (ICM-VLS). In vitro competitive binding assays confirmed that 12 were thermolysin



全球贸易项目编号

货号GTIN
H6878-100G04061833802274
H6878-25G04061833802281
H6878-500G04061833802342