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Merck
CN

L0380000

左旋咪唑 盐酸盐

European Pharmacopoeia (EP) Reference Standard

别名:

(−)-四咪唑 盐酸盐, L(−)- 2,3,5,6-四氢-6-苯基咪唑并[2,1-b]噻唑 盐酸盐, 左旋咪唑 盐酸盐, (S)-(−)-6-苯基-2,3,5,6-四氢咪唑并[2,1-b]噻唑 盐酸盐

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关于此项目

经验公式(希尔记法):
C11H12N2S · HCl
化学文摘社编号:
分子量:
240.75
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
240-654-6
Beilstein/REAXYS Number:
4358988
MDL number:
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grade

pharmaceutical primary standard

API family

levamisole

manufacturer/tradename

EDQM

mp

228-230 °C

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.C1CN2C[C@@H](N=C2S1)c3ccccc3

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1

InChI key

LAZPBGZRMVRFKY-HNCPQSOCSA-N

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。 如需进一步信息和支持,请访问现行药典网站。

Application

盐酸左旋咪唑EP参考标准品的预期用途是欧洲药典规定的实验室测试。

Biochem/physiol Actions

根据一些可控因素,同时显示免疫刺激和免疫抑制作用。治疗蛔虫病(钩虫感染)非常有效。可用于结肠直肠癌的化疗,可能是由于其刺激IL-1 产生和巨噬细胞的直接激活。

Packaging

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

Other Notes

销售限制可能适用。


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ana Mbokeleng Tsotetsi et al.
Tropical animal health and production, 45(3), 751-761 (2012-10-16)
The present study was conducted to determine the prevalence and distribution of gastrointestinal helminths, to detect the presence of anthelmintic resistance in livestock from small-scale farms and to determine the level of helminthosis awareness among small-scale farmers in Gauteng Province
Annemarie Rosan Kreeftmeijer-Vegter et al.
Expert opinion on drug delivery, 10(3), 293-300 (2013-01-08)
To develop an oral solid dosage form of levamisole suitable for the paediatric population in terms of dose accuracy, palatability, stability and ease of administration. Small undividable tablets (Ø5 - 8 mm) in four different strengths were manufactured to allow
David S Lindsay et al.
Veterinary parasitology, 196(1-2), 21-23 (2013-03-26)
Decoquinate is a quinolone anticoccidial approved for use in the prevention of intestinal coccidiosis in farm animals. This compound has good activity against Toxoplasma gondii and Neospora caninum in cell cultures. The drug acts on the parasites' mitochondria. The activity



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货号GTIN
L038000004061833945698